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Literature DB >> 16371778

Continuous measurement of corneal dehydration with online optical coherence pachymetry.

Henning Aurich¹, Christopher Wirbelauer, Jan Jaroszewski, Christian Hartmann, Duy Thoai Pham.

Abstract

PURPOSE: Online optical coherence pachymetry (online OCP) allows continuous central corneal thickness measurements over time. In this study, the effect of dehydration on corneal tissue was investigated with online OCP.
METHODS: Twelve eyes of 11 patients were examined with online OCP, and the central corneal thickness was registered over 5 minutes after insertion of an eyelid speculum.
RESULTS: Online OCP measurements revealed no decrease in reproducibility after 5 minutes of dehydration. The initial mean central corneal thickness was 538 +/- 48 microm. After 5 minutes the central corneal thickness decreased to 483 +/- 43 microm (P = 0.001). This corresponded to a mean corneal thinning of 55 +/- 4 microm (10.2%) at a rate of 0.19 microm/s.
CONCLUSIONS: Online OCP was suitable for continuous measurements of corneal changes caused by dehydration. These dehydration effects should be particularly considered in refractive corneal surgery.

Entities: Disease Species

Mesh：

Year: 2006 PMID： 16371778 DOI： 10.1097/01.ico.0000176610.50461.77

Source DB: PubMed Journal: Cornea ISSN： 0277-3740 Impact factor: 2.651

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Cited

6 in total

1. Comparison of different excimer laser ablation frequencies (50, 200, and 500 Hz).

Authors: C Winkler von Mohrenfels; R Khoramnia; C-P Lohmann
Journal: Graefes Arch Clin Exp Ophthalmol Date: 2009-07-14 Impact factor: 3.117

2. Intraoperative optical coherence tomography to evaluate the effect of the eyelid speculum on corneal pachymetry during accelerated corneal cross-linking (9 mW/cm²).

Authors: R Ghaffari; M Mortazavi; P Anvari; A Salamat Rad; F Alipour; F Hafezi; S Asgari; H Hashemi
Journal: Eye (Lond) Date: 2017-11-24 Impact factor: 3.775

3. Corneal stromal dehydration and optimal stromal exposure time during corneal refractive surgery measured using a three-dimensional optical profiler.

Authors: Yanan Wu; Yan Wang; Zimiao Zhang; Xingchen Yu
Journal: Graefes Arch Clin Exp Ophthalmol Date: 2022-07-25 Impact factor: 3.535

Continuous measurement of corneal dehydration with online optical coherence pachymetry.

1. Comparison of different excimer laser ablation frequencies (50, 200, and 500 Hz).

2. Intraoperative optical coherence tomography to evaluate the effect of the eyelid speculum on corneal pachymetry during accelerated corneal cross-linking (9 mW/cm²).

3. Corneal stromal dehydration and optimal stromal exposure time during corneal refractive surgery measured using a three-dimensional optical profiler.

4. Entrapment of ketorolac tromethamine in polymeric vehicle for controlled drug delivery.

5. Online optical coherence pachymetry to evaluate intraoperative ablation parameters in LASIK.

Review 6. The theory and art of corneal cross-linking.

Continuous measurement of corneal dehydration with online optical coherence pachymetry.

1. Comparison of different excimer laser ablation frequencies (50, 200, and 500 Hz).

2. Intraoperative optical coherence tomography to evaluate the effect of the eyelid speculum on corneal pachymetry during accelerated corneal cross-linking (9 mW/cm2).

3. Corneal stromal dehydration and optimal stromal exposure time during corneal refractive surgery measured using a three-dimensional optical profiler.

4. Entrapment of ketorolac tromethamine in polymeric vehicle for controlled drug delivery.

5. Online optical coherence pachymetry to evaluate intraoperative ablation parameters in LASIK.

Review 6. The theory and art of corneal cross-linking.

2. Intraoperative optical coherence tomography to evaluate the effect of the eyelid speculum on corneal pachymetry during accelerated corneal cross-linking (9 mW/cm²).