Literature DB >> 16366523

Oxygen binding to tyrosinase from streptomyces antibioticus studied by laser flash photolysis.

Shun Hirota1, Takumi Kawahara, Emanuela Lonardi, Ellen de Waal, Noriaki Funasaki, Gerard W Canters.   

Abstract

Tyrosinases catalyze the o-hydroxylation of monophenols (monophenolase activity) and the oxidation of o-diphenols to o-quinones (diphenolase activity) and possess a dinuclear copper active site. The O2 binding kinetics of oxytyrosinase is studied by flash-photolysis measurements, and the O2 binding rate constant (kO2) is obtained as kO2 = 13 +/- 3 muM-1 s-1. Small molecules, such as carbon monoxide and p-nitrophenol (a substrate-analogue inhibitor), are demonstrated to affect O2 binding kinetics. The activation enthalpy of the rate-limiting step of O2 binding is calculated by the temperature dependence of kO2 to be 12.8 +/- 2.6 kcal/mol.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 16366523     DOI： 10.1021/ja0541128

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  6 in total

1.  CO and O2 binding to pseudo-tetradentate ligand-copper(I) complexes with a variable N-donor moiety: kinetic/thermodynamic investigation reveals ligand-induced changes in reaction mechanism.

Authors:  Heather R Lucas; Gerald J Meyer; Kenneth D Karlin
Journal:  J Am Chem Soc       Date:  2010-09-22       Impact factor: 15.419

Review 2.  Copper active sites in biology.

Authors:  Edward I Solomon; David E Heppner; Esther M Johnston; Jake W Ginsbach; Jordi Cirera; Munzarin Qayyum; Matthew T Kieber-Emmons; Christian H Kjaergaard; Ryan G Hadt; Li Tian
Journal:  Chem Rev       Date:  2014-03-03       Impact factor: 60.622

3.  Structural basis of the lactate-dependent allosteric regulation of oxygen binding in arthropod hemocyanin.

Authors:  Shun Hirota; Naoki Tanaka; Ivan Micetic; Paolo Di Muro; Satoshi Nagao; Hiroaki Kitagishi; Koji Kano; Richard S Magliozzo; Jack Peisach; Mariano Beltramini; Luigi Bubacco
Journal:  J Biol Chem       Date:  2010-04-20       Impact factor: 5.157

4.  Evidence for H-bonding interactions to the μ-η2:η2-peroxide of oxy-tyrosinase that activate its coupled binuclear copper site.

Authors:  Ioannis Kipouros; Agnieszka Stańczak; Martin Culka; Erik Andris; Timothy R Machonkin; Lubomír Rulíšek; Edward I Solomon
Journal:  Chem Commun (Camb)       Date:  2022-03-22       Impact factor: 6.222

5.  Laser-Induced Dynamics of Peroxodicopper(II) Complexes Vary with the Ligand Architecture. One-Photon Two-Electron O2 Ejection and Formation of Mixed-Valent Cu(I)Cu(II)-Superoxide Intermediates.

Authors:  Claudio Saracini; Kei Ohkubo; Tomoyoshi Suenobu; Gerald J Meyer; Kenneth D Karlin; Shunichi Fukuzumi
Journal:  J Am Chem Soc       Date:  2015-12-11       Impact factor: 15.419

6.  Molecular basis of the Bohr effect in arthropod hemocyanin.

Authors:  Shun Hirota; Takumi Kawahara; Mariano Beltramini; Paolo Di Muro; Richard S Magliozzo; Jack Peisach; Linda S Powers; Naoki Tanaka; Satoshi Nagao; Luigi Bubacco
Journal:  J Biol Chem       Date:  2008-08-25       Impact factor: 5.157
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.