| Literature DB >> 16364642 |
Romano Di Fabio1, Riccardo Giovannini, Barbara Bertani, Manuela Borriello, Andrea Bozzoli, Daniele Donati, Alessandro Falchi, Damiano Ghirlanda, Colin P Leslie, Angelo Pecunioso, Giovanna Rumboldt, Simone Spada.
Abstract
The SAR of a new series of tetrahydrocarbazole derivatives is described: the appropriate decoration of this template led to the identification of a new class of NPY-1 antagonists showing good in vitro potency and a promising in vivo pharmacokinetic profile in rat.Entities:
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Year: 2005 PMID： 16364642 DOI： 10.1016/j.bmcl.2005.11.104
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823