Literature DB >> 16360557

Explained variation in a model of therapeutic decision making is partitioned across patient, physician, and clinic factors.

M Alan Brookhart1, Daniel H Solomon, Philip Wang, Robert J Glynn, Jerry Avorn, Sebastian Schneeweiss.   

Abstract

BACKGROUND AND
OBJECTIVE: Data on therapeutic decision making have a multilevel structure that can include patient-, provider-, and facility-level variables. A statistical method is presented for attributing explained variation in patient care to different levels of aggregation in a multilevel model with the aim of prioritizing and targeting quality improvement interventions. STUDY DESIGN AND
SETTING: The proposed method is used in an analysis of adherence to evidence-based guidelines for the care of patients at risk of osteoporosis. Explained variation from a multilevel model of appropriate care is partitioned across patient-, physician-, and clinic-level factors.
RESULTS: The combination of patient, physician, and clinic factors explained 20.0% of the variation in patient care. Individual physician effects explained 14.0% of the variation in the data; however, more than half of this explained variation could have been attributed to the individual clinic effect. Patient fixed effects alone explained 13.4% of the variation in the observed clinical decisions.
CONCLUSION: The proposed approach is an intuitive and statistically valid method for attributing explained variation in a multilevel analysis of therapeutic decision making.

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Year:  2005        PMID: 16360557     DOI: 10.1016/j.jclinepi.2005.07.005

Source DB:  PubMed          Journal:  J Clin Epidemiol        ISSN: 0895-4356            Impact factor:   6.437


  16 in total

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Authors:  S Schneeweiss
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2.  Variation in nephrologist visits to patients on hemodialysis across dialysis facilities and geographic locations.

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3.  Adherence of academic geriatric practitioners to osteoporosis screening guidelines.

Authors:  D N McNally; A M Kenny; J-A Smith
Journal:  Osteoporos Int       Date:  2006-10-17       Impact factor: 4.507

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5.  Correlations of nursing home characteristics with prescription of osteoporosis medications.

Authors:  Seema Parikh; M Alan Brookhart; Margaret Stedman; Jerry Avorn; Helen Mogun; Daniel H Solomon
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8.  Do physicians within the same practice setting manage osteoporosis patients similarly? Implications for implementation research.

Authors:  J R Curtis; T Arora; J Xi; A Silver; J J Allison; L Chen; K G Saag; A Schenck; A O Westfall; C Colón-Emeric
Journal:  Osteoporos Int       Date:  2009-03-25       Impact factor: 4.507

9.  Therapeutic traditions, patient socioeconomic characteristics and physicians' early new drug prescribing--a multilevel analysis of rosuvastatin prescription in south Sweden.

Authors:  Henrik Ohlsson; Basile Chaix; Juan Merlo
Journal:  Eur J Clin Pharmacol       Date:  2008-10-04       Impact factor: 2.953

10.  Patient-Reported Experiences of Dialysis Care Within a National Pay-for-Performance System.

Authors:  Brian M Brady; Bo Zhao; Jingbo Niu; Wolfgang C Winkelmayer; Arnold Milstein; Glenn M Chertow; Kevin F Erickson
Journal:  JAMA Intern Med       Date:  2018-10-01       Impact factor: 21.873

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