Literature DB >> 16358042

Fluorescence based strategies for genetic analysis.

Rohan T Ranasinghe1, Tom Brown.   

Abstract

Synthetic chemistry has been central to the design of modern methods of genetic analysis. In this article, we discuss the underlying chemistry and biophysical principles that have been used in the development of robust methods for the analysis of DNA in the diagnostic laboratory.

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Year:  2005        PMID： 16358042     DOI： 10.1039/b509522k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  33 in total

1.  New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymes.

Authors:  Afaf H El-Sagheer; Tom Brown
Journal:  Proc Natl Acad Sci U S A       Date:  2010-08-16       Impact factor: 11.205

2.  Fluorescent pyrimidine ribonucleotide: synthesis, enzymatic incorporation, and utilization.

Authors:  Seergazhi G Srivatsan; Yitzhak Tor
Journal:  J Am Chem Soc       Date:  2007-01-26       Impact factor: 15.419

3.  PNA HyBeacons for analysis of human mutations related to statin-induced myopathy.

Authors:  Nittaya Gale; Petr Kocalka; Charlotte Mardle; Tom Brown
Journal:  Artif DNA PNA XNA       Date:  2011 Jul-Dec

4.  Using an emissive uridine analogue for assembling fluorescent HIV-1 TAR constructs.

Authors:  Seergazhi G Srivatsan; Yitzhak Tor
Journal:  Tetrahedron       Date:  2007-04-23       Impact factor: 2.457

Review 5.  Fluorescent analogs of biomolecular building blocks: design, properties, and applications.

Authors:  Renatus W Sinkeldam; Nicholas J Greco; Yitzhak Tor
Journal:  Chem Rev       Date:  2010-05-12       Impact factor: 60.622

6.  Comparative Study of Novel Fluorescent Cyanine Nucleotides: Hybridization Analysis of Labeled PCR Products Using a Biochip.

Authors:  V E Shershov; S A Lapa; V E Kuznetsova; M A Spitsyn; T O Guseinov; S A Polyakov; A A Stomahin; A S Zasedatelev; A V Chudinov
Journal:  J Fluoresc       Date:  2017-07-28       Impact factor: 2.217

Review 7.  Chemistry of nucleic acids: impacts in multiple fields.

Authors:  Omid Khakshoor; Eric T Kool
Journal:  Chem Commun (Camb)       Date:  2011-04-11       Impact factor: 6.222

8.  Enzymatic incorporation of emissive pyrimidine ribonucleotides.

Authors:  Seergazhi G Srivatsan; Yitzhak Tor
Journal:  Chem Asian J       Date:  2009-03-02

9.  Synthetic incorporation of Nile Blue into DNA using 2'-deoxyriboside substitutes: Representative comparison of (R)- and (S)-aminopropanediol as an acyclic linker.

Authors:  Daniel Lachmann; Sina Berndl; Otto S Wolfbeis; Hans-Achim Wagenknecht
Journal:  Beilstein J Org Chem       Date:  2010-02-09       Impact factor: 2.883

10.  Functionalized 2'-amino-alpha-L-LNA: directed positioning of intercalators for DNA targeting.

Authors:  T Santhosh Kumar; Andreas S Madsen; Michael E Østergaard; Sujay P Sau; Jesper Wengel; Patrick J Hrdlicka
Journal:  J Org Chem       Date:  2009-02-06       Impact factor: 4.354
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