Literature DB >> 16357427

An RF phased array applicator designed for hyperthermia breast cancer treatments.

Liyong Wu1, Robert J McGough, Omar Ali Arabe, Thaddeus V Samulski.   

Abstract

An RF phased array applicator has been constructed for hyperthermia treatments in the intact breast. This RF phased array consists of four antennas mounted on a Lexan water tank, and geometric focusing is employed so that each antenna points in the direction of the intended target. The operating frequency for this phased array is 140 MHz. The RF array has been characterized both by electric field measurements in a water tank and by electric field simulations using the finite-element method. The finite-element simulations are performed with HFSS software, where the mesh defined for finite-element calculations includes the geometry of the tank enclosure and four end-loaded dipole antennas. The material properties of the water tank enclosure and the antennas are also included in each simulation. The results of the finite-element simulations are compared to the measured values for this configuration, and the results, which include the effects of amplitude shading and phase shifting, show that the electric field predicted by finite-element simulations is similar to the measured field. Simulations also show that the contributions from standing waves are significant, which is consistent with measurement results. Simulated electric field and bio-heat transfer results are also computed within a simple 3D breast model. Temperature simulations show that, although peak temperatures are generated outside the simulated tumour target, this RF phased array applicator is an effective device for regional hyperthermia in the intact breast.

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Year:  2005        PMID: 16357427      PMCID: PMC2444040          DOI: 10.1088/0031-9155/51/1/001

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  32 in total

1.  A flexible optimization tool for hyperthermia treatments with RF phased array systems.

Authors:  J Wiersma; R A M van Maarseveen; J D P van Dijk
Journal:  Int J Hyperthermia       Date:  2002 Mar-Apr       Impact factor: 3.914

Review 2.  Comprehensive management of locally advanced breast cancer.

Authors:  G N Hortobagyi
Journal:  Cancer       Date:  1990-09-15       Impact factor: 6.860

3.  Theoretical electric field distributions produced by three types of regional hyperthermia devices in a three-dimensional homogeneous model of man.

Authors:  K D Paulsen; J W Strohbehn; D R Lynch
Journal:  IEEE Trans Biomed Eng       Date:  1988-01       Impact factor: 4.538

4.  Strategies for optimized application of annular-phased-array systems in clinical hyperthermia.

Authors:  P Wust; J Nadobny; R Felix; P Deuflhard; A Louis; W John
Journal:  Int J Hyperthermia       Date:  1991 Jan-Feb       Impact factor: 3.914

5.  An RF concentrating method using inductive aperture-type applicators.

Authors:  Y Fujita; H Kato; T Ishida
Journal:  IEEE Trans Biomed Eng       Date:  1993-01       Impact factor: 4.538

6.  Computational techniques for fast hyperthermia temperature optimization.

Authors:  S K Das; S T Clegg; T V Samulski
Journal:  Med Phys       Date:  1999-02       Impact factor: 4.071

7.  An on-line phase measurement system for quality assurance of the BSD 2000. Part II: results of the phase measurement system.

Authors:  U Lamprecht; C Gromoll; T Hehr; M Buchgeister; M Bamberg
Journal:  Int J Hyperthermia       Date:  2000 Jul-Aug       Impact factor: 3.914

8.  Magnetic resonance thermometry during hyperthermia for human high-grade sarcoma.

Authors:  D L Carter; J R MacFall; S T Clegg; X Wan; D M Prescott; H C Charles; T V Samulski
Journal:  Int J Radiat Oncol Biol Phys       Date:  1998-03-01       Impact factor: 7.038

9.  Edge-element based finite element analysis of microwave hyperthermia treatments for superficial tumours on the chest wall.

Authors:  J C Kumaradas; M D Sherar
Journal:  Int J Hyperthermia       Date:  2003 Jul-Aug       Impact factor: 3.914

Review 10.  Heating the patient: a promising approach?

Authors:  J van der Zee
Journal:  Ann Oncol       Date:  2002-08       Impact factor: 32.976

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  12 in total

1.  A phase I/II study of neoadjuvant liposomal doxorubicin, paclitaxel, and hyperthermia in locally advanced breast cancer.

Authors:  Zeljko Vujaskovic; Dong W Kim; Ellen Jones; Lan Lan; Linda McCall; Mark W Dewhirst; Oana Craciunescu; Paul Stauffer; Vlayka Liotcheva; Allison Betof; Kimberly Blackwell
Journal:  Int J Hyperthermia       Date:  2010       Impact factor: 3.914

2.  Hyperthermia MRI temperature measurement: evaluation of measurement stabilisation strategies for extremity and breast tumours.

Authors:  Cory Wyatt; Brian Soher; Paolo Maccarini; H Cecil Charles; Paul Stauffer; James Macfall
Journal:  Int J Hyperthermia       Date:  2009       Impact factor: 3.914

3.  Mild hyperthermia with magnetic resonance-guided high-intensity focused ultrasound for applications in drug delivery.

Authors:  Ari Partanen; Pavel S Yarmolenko; Antti Viitala; Sunil Appanaboyina; Dieter Haemmerich; Ashish Ranjan; Genevieve Jacobs; David Woods; Julia Enholm; Bradford J Wood; Matthew R Dreher
Journal:  Int J Hyperthermia       Date:  2012       Impact factor: 3.914

4.  A heterogeneous human tissue mimicking phantom for RF heating and MRI thermal monitoring verification.

Authors:  Yu Yuan; Cory Wyatt; Paolo Maccarini; Paul Stauffer; Oana Craciunescu; James Macfall; Mark Dewhirst; Shiva K Das
Journal:  Phys Med Biol       Date:  2012-03-20       Impact factor: 3.609

5.  Reduction of peak acoustic pressure and shaping of heated region by use of multifoci sonications in MR-guided high-intensity focused ultrasound mediated mild hyperthermia.

Authors:  Ari Partanen; Matti Tillander; Pavel S Yarmolenko; Bradford J Wood; Matthew R Dreher; Max O Kohler
Journal:  Med Phys       Date:  2013-01       Impact factor: 4.071

Review 6.  Heating technology for malignant tumors: a review.

Authors:  H Petra Kok; Erik N K Cressman; Wim Ceelen; Christopher L Brace; Robert Ivkov; Holger Grüll; Gail Ter Haar; Peter Wust; Johannes Crezee
Journal:  Int J Hyperthermia       Date:  2020       Impact factor: 3.914

7.  A radio-frequency coupling network for heating of citrate-coated gold nanoparticles for cancer therapy: design and analysis.

Authors:  Dustin E Kruse; Douglas N Stephens; Heather A Lindfors; Elizabeth S Ingham; Eric E Paoli; Katherine W Ferrara
Journal:  IEEE Trans Biomed Eng       Date:  2011-03-10       Impact factor: 4.538

8.  Towards the Validation of a Commercial Hyperthermia Treatment Planning System.

Authors:  Zhen Li; Martin Vogel; Paolo F Maccarini; Omar A Arabe; Vadim Stakhursky; Devin Crawford; Williams T Joines; Paul R Stauffer
Journal:  Microw J (Int Ed)       Date:  2008       Impact factor: 0.306

9.  DCE-MRI parameters have potential to predict response of locally advanced breast cancer patients to neoadjuvant chemotherapy and hyperthermia: a pilot study.

Authors:  Oana I Craciunescu; Kimberly L Blackwell; Ellen L Jones; James R Macfall; Daohai Yu; Zeljko Vujaskovic; Terence Z Wong; Vlayka Liotcheva; Eric L Rosen; Leonard R Prosnitz; Thaddeus V Samulski; Mark W Dewhirst
Journal:  Int J Hyperthermia       Date:  2009       Impact factor: 3.914

Review 10.  Applications of elastin-like polypeptides in drug delivery.

Authors:  Sarah R MacEwan; Ashutosh Chilkoti
Journal:  J Control Release       Date:  2014-06-28       Impact factor: 9.776

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