Literature DB >> 16355214

Angiogenesis as a therapeutic target.

Napoleone Ferrara1, Robert S Kerbel.   

Abstract

Inhibiting angiogenesis is a promising strategy for treatment of cancer and several other disorders, including age-related macular degeneration. Major progress towards a treatment has been achieved over the past few years, and the first antiangiogenic agents have been recently approved for use in several countries. Therapeutic angiogenesis (promoting new vessel growth to treat ischaemic disorders) is an exciting frontier of cardiovascular medicine, but further understanding of the mechanisms of vascular morphogenesis is needed first.

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Year:  2005        PMID： 16355214     DOI： 10.1038/nature04483

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  854 in total

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