Literature DB >> 16354830

Short report: impact of ivermectin community-level treatments on elimination of adult Onchocerca volvulus when individuals receive multiple treatments per year.

Eddie W Cupp1, Mary S Cupp.   

Abstract

A reanalysis of several published reports indicates that when community-wide biannual treatment disrupts transmission of new infection, a profound macrofilaricidal effect of ivermectin (Mectizan) occurs that is accelerated for individuals treated 4 times a year (4x/yr). The effect is particularly obvious on adult male worms and suggests that this gender is susceptible to repetitive treatment after transmission has been blocked or greatly reduced as a result of community treatment.

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Year:  2005        PMID： 16354830

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  31 in total

1.  Seventeen years of annual distribution of ivermectin has not interrupted onchocerciasis transmission in North Region, Cameroon.

Authors:  Moses N Katabarwa; Albert Eyamba; Philippe Nwane; Peter Enyong; Souleymanou Yaya; Jean Baldiagaï; Théodore Kambaba Madi; Abdoulaye Yougouda; Gervais Ondobo Andze; Frank O Richards
Journal:  Am J Trop Med Hyg       Date:  2011-12       Impact factor: 2.345

2.  Transmission of Onchocerca volvulus by Simulium neavei in Mount Elgon focus of Eastern Uganda has been interrupted.

Authors:  Moses Katabarwa; Tom Lakwo; Peace Habomugisha; Stella Agunyo; Edson Byamukama; David Oguttu; Richard Ndyomugyenyi; Ephraim Tukesiga; Galex Orukan Ochieng; Francis Abwaimo; Ambrose Onapa; Dennis W K Lwamafa; Frank Walsh; Thomas R Unnasch; Frank O Richards
Journal:  Am J Trop Med Hyg       Date:  2014-03-31       Impact factor: 2.345

3.  A computational analysis of the binding mode of closantel as inhibitor of the Onchocerca volvulus chitinase: insights on macrofilaricidal drug design.

Authors:  Aldo Segura-Cabrera; Virgilio Bocanegra-García; Cristian Lizarazo-Ortega; Xianwu Guo; José Correa-Basurto; Mario A Rodríguez-Pérez
Journal:  J Comput Aided Mol Des       Date:  2011-11-19       Impact factor: 3.686

Review 4.  Zoonotic Onchocerca lupi infection in a 22-month-old child in Arizona: first report in the United States and a review of the literature.

Authors:  Mark L Eberhard; Gholamabbas Amin Ostovar; Kote Chundu; Dan Hobohm; Iman Feiz-Erfan; Blaine A Mathison; Henry S Bishop; Paul T Cantey
Journal:  Am J Trop Med Hyg       Date:  2013-02-04       Impact factor: 2.345

5.  Canine ocular onchocerciasis: a retrospective review of the diagnosis, treatment, and outcome of 16 cases in New Mexico (2011-2015).

Authors:  Nancy Johnstone McLean; Kimberly Newkirk; Coenraad M Adema
Journal:  Vet Ophthalmol       Date:  2016-09-13       Impact factor: 1.644

6.  The Emergence of Zoonotic Onchocerca lupi Infection in the United States--A Case-Series.

Authors:  Paul T Cantey; Jessica Weeks; Morven Edwards; Suchitra Rao; G Amin Ostovar; Walter Dehority; Maria Alzona; Sara Swoboda; Brooke Christiaens; Wassim Ballan; John Hartley; Andrew Terranella; Jill Weatherhead; James J Dunn; Douglas P Marx; M John Hicks; Ronald A Rauch; Christiana Smith; Megan K Dishop; Michael H Handler; Roy W R Dudley; Kote Chundu; Dan Hobohm; Iman Feiz-Erfan; Joseph Hakes; Ryan S Berry; Shelly Stepensaski; Benjamin Greenfield; Laura Shroeder; Henry Bishop; Marcos de Almeida; Blaine Mathison; Mark Eberhard
Journal:  Clin Infect Dis       Date:  2015-11-26       Impact factor: 9.079

7.  Rapid suppression of Onchocerca volvulus transmission in two communities of the Southern Chiapas focus, Mexico, achieved by quarterly treatments with Mectizan.

Authors:  Mario A Rodríguez-Pérez; Miguel A Lutzow-Steiner; Aldo Segura-Cabrera; Cristian Lizarazo-Ortega; Alfredo Domínguez-Vázquez; Mauricio Sauerbrey; Frank Richards; Thomas R Unnasch; Hassan K Hassan; Raymundo Hernández-Hernández
Journal:  Am J Trop Med Hyg       Date:  2008-08       Impact factor: 2.345

8.  One Hundred Years After Its Discovery in Guatemala by Rodolfo Robles, Onchocerca volvulus Transmission Has Been Eliminated from the Central Endemic Zone.

Authors:  Frank Richards; Nidia Rizzo; Carlos Enrique Diaz Espinoza; Zoraida Morales Monroy; Carol Guillermina Crovella Valdez; Renata Mendizabal de Cabrera; Oscar de Leon; Guillermo Zea-Flores; Mauricio Sauerbrey; Alba Lucia Morales; Dalila Rios; Thomas R Unnasch; Hassan K Hassan; Robert Klein; Mark Eberhard; Ed Cupp; Alfredo Domínguez
Journal:  Am J Trop Med Hyg       Date:  2015-10-26       Impact factor: 2.345

9.  Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study.

Authors:  Achim Hoerauf; Sabine Specht; Marcelle Büttner; Kenneth Pfarr; Sabine Mand; Rolf Fimmers; Yeboah Marfo-Debrekyei; Peter Konadu; Alexander Yaw Debrah; Claudio Bandi; Norbert Brattig; Anna Albers; John Larbi; Linda Batsa; Mark J Taylor; Ohene Adjei; Dietrich W Büttner
Journal:  Med Microbiol Immunol       Date:  2007-11-13       Impact factor: 3.402

10.  How does onchocerciasis-related skin and eye disease in Africa depend on cumulative exposure to infection and mass treatment?

Authors:  Natalie V S Vinkeles Melchers; Wilma A Stolk; Michele E Murdoch; Belén Pedrique; Marielle Kloek; Roel Bakker; Sake J de Vlas; Luc E Coffeng
Journal:  PLoS Negl Trop Dis       Date:  2021-06-11
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