| Literature DB >> 16351589 |
Jasminko Huskić1, Alma Paperniku, Azra Husić, Faruk Alendar, Nedzad Mulabegović.
Abstract
In order to study concentration of nitric oxide (NO) in the saliva of patients with Parkinson's disease (PD), we measured the concentration of its stable metabolite nitrite (NO(2)-) in the saliva of these patients and healthy subjects. We analyzed saliva flow rate and salivary NO concentrations in 16 subjects with Parkinson's disease and in 16 healthy subjects. Concentration of nitrite was determined by colorimetric method using Griess reaction. Saliva flow rate was significantly lower in patients with Parkinson's disease (0.2+/-0.03 mL/min; X+/-SEM) than in healthy subjects. Salivary NO(2)-concentration was significantly lower (5.02+/-0.64) than in healthy individuals (22.39+/-1.24, p<0.0001).Entities:
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Year: 2005 PMID： 16351589 PMCID： PMC7202145 DOI： 10.17305/bjbms.2005.3277
Source DB: PubMed Journal: Bosn J Basic Med Sci ISSN： 1512-8601 Impact factor: 3.363