Literature DB >> 16339705

Allosensitization in patients receiving multiple blood transfusions.

V S Sakhalkar1, K Roberts, L M Hawthorne, D M McCaskill, D M Veillon, G C Caldito, J D Cotelingam.   

Abstract

Extended antigen (C, E, K) matching decreased the incidence of alloantibody (alloAB) and autoantibody (autoAB) formation, in addition to eliminating transfusion reactions in the multiply transfused sickle cell disease patients. AlloAB formation possibly transforms the immune system into a hyperactive state leading to further and earlier alloAB and autoAB formation. However, additional CEK matching results in marked overuse of Rh-negative packed red blood cell (pRBC) units, 30 minutes' extra time of a skilled technologist, and 153 dollars extra CEK reagent cost per unit to find CEK-matched pRBCs for every transfusion for these multiply transfused patients.

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Year:  2005        PMID： 16339705     DOI： 10.1196/annals.1345.072

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  18 in total

1.  Red Blood Cell Alloimmunization in Multitransfused Pediatric Population in a Tertiary Care Hospital.

Authors:  A P Poornima; Shiffi Fazal; P S Shaiji; K C Usha; Lalitha Kailas
Journal:  Indian J Pediatr       Date:  2018-12-04       Impact factor: 1.967

2.  Duffy genotyping facilitates transfusion therapy.

Authors:  Carlos Cotorruelo; Claudia Biondi; Liliana Racca; Silvia García Borrás; Amelia Racca
Journal:  Clin Exp Med       Date:  2009-02-19       Impact factor: 3.984

3.  Rh alloimmunization in chronically transfused patients with thalassemia receiving RhD, C, E, and K matched transfusions.

Authors:  Sarah J Waldis; Stacey Uter; Donna Kavitsky; Cynthia Flickinger; Sunitha Vege; David F Friedman; Connie M Westhoff; Stella T Chou
Journal:  Blood Adv       Date:  2021-02-09

Review 4.  Transfusion in Haemoglobinopathies: Review and recommendations for local blood banks and transfusion services in Oman.

Authors:  Arwa Z Al-Riyami; Shahina Daar
Journal:  Sultan Qaboos Univ Med J       Date:  2018-04-04

5.  Diversity of RH and transfusion support in Brazilian sickle cell disease patients with unexplained Rh antibodies.

Authors:  Carla L Dinardo; Shannon Kelly; Marcia R Dezan; Ingrid H Ribeiro; Shirley L Castilho; Luciana C Schimidt; Maria do C Valgueiro; Liliana R Preiss; Brian Custer; Ester C Sabino; Connie M Westhoff
Journal:  Transfusion       Date:  2019-08-13       Impact factor: 3.157

Review 6.  Genotyping Applications for Transplantation and Transfusion Management: The Emory Experience.

Authors:  Ross M Fasano; Harold Cliff Sullivan; Robert A Bray; Howard M Gebel; Erin K Meyer; Annie M Winkler; Cassandra D Josephson; Sean R Stowell; Alexander Sandy Duncan; John D Roback
Journal:  Arch Pathol Lab Med       Date:  2017-03       Impact factor: 5.534

7.  Economic evaluation of a hypothetical screening assay for alloimmunization risk among transfused patients with sickle cell disease.

Authors:  Seema Kacker; Paul M Ness; William J Savage; Kevin D Frick; R Sue Shirey; Karen E King; Aaron A R Tobian
Journal:  Transfusion       Date:  2014-02-27       Impact factor: 3.157

8.  Cost-effectiveness of prospective red blood cell antigen matching to prevent alloimmunization among sickle cell patients.

Authors:  Seema Kacker; Paul M Ness; William J Savage; Kevin D Frick; R Sue Shirey; Karen E King; Aaron A R Tobian
Journal:  Transfusion       Date:  2013-05-21       Impact factor: 3.157

Review 9.  Red Cell Transfusions in the Genomics Era.

Authors:  Jamal H Carter; Willy A Flegel
Journal:  Semin Hematol       Date:  2019-11-08       Impact factor: 3.851

10.  Transfusion Support in Patients with Hematologic Disease: New and Novel Transfusion Modalities.

Authors:  Sandhya R Panch; Bipin N Savani; David F Stroncek
Journal:  Semin Hematol       Date:  2019-10       Impact factor: 3.851
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