BACKGROUND AND PURPOSE: As stroke mortality rates decline, individuals are increasingly likely to live with their residual impairments and disabilities. Therefore, the quality of poststroke life is 1 of the pivotal topics that have to be considered beneath the functional outcome. However, data on health-related quality of life (HRQoL) have been infrequently used in stroke trials. The purpose of this study was to examine the long-term outcome (4 years after stroke) of HRQoL and to identify the determinants of HRQoL in stroke survivors. METHODS: Seventy-seven patients were included who were admitted to the Department of Neurology, Philipps-University Marburg, after experiencing an ischemic stroke, a transient ischemic attack, or a hemorrhagic stroke. All patients were examined by a physician, and assessment was performed using a standardized questionnaire. HRQoL was assessed using the German version of the EuroQoL Index (EQ-5D) and the Health Utility Index 2 and 3 (HUI2/3). RESULTS: Four years after stroke, besides physical functioning, neuropsychological sequelae such as depression and cognitive impairment contributed to a reduced HRQoL. In addition, the incidence of incontinence proved to be an important factor for HRQoL. Explained variances in regression analysis models were high (R2=0.802 for HUI and 0.633 for EQ-5D--visual analogue scale) and were based on a few important determinants, including physical state, depression, cognitive impairment, and incontinence. CONCLUSIONS: Our results underscore the importance of nonmotor symptoms on HRQoL in patients with stroke.
BACKGROUND AND PURPOSE: As stroke mortality rates decline, individuals are increasingly likely to live with their residual impairments and disabilities. Therefore, the quality of poststroke life is 1 of the pivotal topics that have to be considered beneath the functional outcome. However, data on health-related quality of life (HRQoL) have been infrequently used in stroke trials. The purpose of this study was to examine the long-term outcome (4 years after stroke) of HRQoL and to identify the determinants of HRQoL in stroke survivors. METHODS: Seventy-seven patients were included who were admitted to the Department of Neurology, Philipps-University Marburg, after experiencing an ischemic stroke, a transient ischemic attack, or a hemorrhagic stroke. All patients were examined by a physician, and assessment was performed using a standardized questionnaire. HRQoL was assessed using the German version of the EuroQoL Index (EQ-5D) and the Health Utility Index 2 and 3 (HUI2/3). RESULTS: Four years after stroke, besides physical functioning, neuropsychological sequelae such as depression and cognitive impairment contributed to a reduced HRQoL. In addition, the incidence of incontinence proved to be an important factor for HRQoL. Explained variances in regression analysis models were high (R2=0.802 for HUI and 0.633 for EQ-5D--visual analogue scale) and were based on a few important determinants, including physical state, depression, cognitive impairment, and incontinence. CONCLUSIONS: Our results underscore the importance of nonmotor symptoms on HRQoL in patients with stroke.
Authors: Elen B Pinto; Iara Maso; Julio L B Pereira; Thiago G Fukuda; Jamile C Seixas; Daniela F Menezes; Carolina Cincura; Iuri S Neville; Pedro A P Jesus; Jamary Oliveira-Filho Journal: Health Qual Life Outcomes Date: 2011-08-10 Impact factor: 3.186
Authors: Tanzila Shams; Alexander P Auchus; Suzanne Oparil; Clinton B Wright; Jackson Wright; Anthony J Furlan; Cathy A Sila; Barry R Davis; Sara Pressel; Jose-Miguel Yamal; Paula T Einhorn; Alan J Lerner Journal: Stroke Date: 2017-09-27 Impact factor: 7.914
Authors: Binith Cheeran; Leonardo Cohen; Bruce Dobkin; Gary Ford; Richard Greenwood; David Howard; Masud Husain; Malcolm Macleod; Randolph Nudo; John Rothwell; Anthony Rudd; James Teo; Nicholas Ward; Steven Wolf Journal: Neurorehabil Neural Repair Date: 2009-02 Impact factor: 3.919
Authors: Anupam Gupta; S Deepika; A B Taly; Abhishek Srivastava; Vishal Surender; Murali Thyloth Journal: Ann Indian Acad Neurol Date: 2008-10 Impact factor: 1.383
Authors: Matthew T D Dyer; Kimberley A Goldsmith; Linda S Sharples; Martin J Buxton Journal: Health Qual Life Outcomes Date: 2010-01-28 Impact factor: 3.186