Literature DB >> 16332508

Antiviral and immunoregulatory effect of a novel exopolysaccharide from a marine thermotolerant Bacillus licheniformis.

Adriana Arena1, Teresa L Maugeri, Bernadette Pavone, Daniela Iannello, Concetta Gugliandolo, Giuseppe Bisignano.   

Abstract

EPS-1 is a novel extracellular polysaccharide produced by a strain of thermotolerant Bacillus licheniformis, isolated from a shallow marine hot spring of Vulcano Island (Italy). In this paper, antiviral and immunomodulatory effects of EPS-1 were evaluated. It was found that EPS-1 treatment impaired HSV-2 replication in human peripheral blood mononuclear cells (PBMC) but not in WISH cells. Since several cytokines modulate the immune response to viruses, Th1- and Th2-type cytokines were assayed in supernatants of PBMC in different experimental conditions. EPS-1 induced IL-12, IFN-gamma, IFN-alpha, TNF-alpha and IL-18, but not IL-4. Thus, the antiviral effect of EPS-1 on PBMC seems to be related to the pattern of cytokines induced.

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Year:  2005        PMID： 16332508     DOI： 10.1016/j.intimp.2005.07.004

Source DB:  PubMed          Journal:  Int Immunopharmacol        ISSN： 1567-5769            Impact factor:   4.932


  34 in total

Review 1.  Role of Marine Natural Products in the Genesis of Antiviral Agents.

Authors:  Vedanjali Gogineni; Raymond F Schinazi; Mark T Hamann
Journal:  Chem Rev       Date:  2015-08-28       Impact factor: 60.622

2.  Structural characterization of Bacillus licheniformis Dahb1 exopolysaccharide-antimicrobial potential and larvicidal activity on malaria and Zika virus mosquito vectors.

Authors:  Muthukumar Abinaya; Baskaralingam Vaseeharan; Mani Divya; Sekar Vijayakumar; Marimuthu Govindarajan; Naiyf S Alharbi; Jamal M Khaled; Mohammed N Al-Anbr; Giovanni Benelli
Journal:  Environ Sci Pollut Res Int       Date:  2018-04-27       Impact factor: 4.223

3.  Production and chemical characterization of an exopolysaccharide synthesized by psychrophilic yeast strain Sporobolomyces salmonicolor AL₁ isolated from Livingston Island, Antarctica.

Authors:  A Poli; G Anzelmo; G Tommonaro; K Pavlova; A Casaburi; B Nicolaus
Journal:  Folia Microbiol (Praha)       Date:  2011-01-21       Impact factor: 2.099

4.  In Vitro Antibiofilm Activity of an Exopolysaccharide from the Marine Thermophilic Bacillus licheniformis T14.

Authors:  Antonio Spanò; Pasqualina Laganà; Giuseppa Visalli; Teresa L Maugeri; Concetta Gugliandolo
Journal:  Curr Microbiol       Date:  2016-01-11       Impact factor: 2.188

5.  Extraction and characterization of an exopolysaccharide from a marine bacterium.

Authors:  Bythadka Erappa Dhanya; Ashwini Prabhu; Punchappady Devasya Rekha
Journal:  Int Microbiol       Date:  2021-10-19       Impact factor: 2.479

6.  Production, structural and biochemical characterization relevant to antitumor property of acidic exopolysaccharide produced from Bacillus sp. NRC5.

Authors:  Sahar S Mohamed; Abeer Y Ibrahim; Mohsen S Asker; Manal G Mahmoud; Samah A El-Newary
Journal:  Arch Microbiol       Date:  2021-06-10       Impact factor: 2.552

7.  A novel EPS-producing strain of Bacillus licheniformis isolated from a shallow vent off Panarea Island (Italy).

Authors:  Antonio Spanò; Concetta Gugliandolo; Valeria Lentini; Teresa L Maugeri; Gianluca Anzelmo; Annarita Poli; Barbara Nicolaus
Journal:  Curr Microbiol       Date:  2013-02-10       Impact factor: 2.188

Review 8.  Marine pharmacology in 2005-6: Marine compounds with anthelmintic, antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems, and other miscellaneous mechanisms of action.

Authors:  Alejandro M S Mayer; Abimael D Rodríguez; Roberto G S Berlinck; Mark T Hamann
Journal:  Biochim Biophys Acta       Date:  2009-03-19

Review 9.  Bacterial exopolysaccharides from extreme marine habitats: production, characterization and biological activities.

Authors:  Annarita Poli; Gianluca Anzelmo; Barbara Nicolaus
Journal:  Mar Drugs       Date:  2010-06-03       Impact factor: 5.118

10.  Activation of Macrophages by Exopolysaccharide Produced by MK1 Bacterial Strain Isolated from Neungee Mushroom, Sarcodon aspratus.

Authors:  Sun-A Im; Wenxia Wang; Chong-Kil Lee; Young Nam Lee
Journal:  Immune Netw       Date:  2010-12-31       Impact factor: 6.303
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