Literature DB >> 16317214

Integrating behavioral and social science research into microbicide clinical trials: challenges and opportunities.

Elizabeth E Tolley1, Lawrence J Severy.   

Abstract

It has been argued that rigid thinking about the types and progression of research needed to evaluate health promotion interventions has stymied the process by which research is translated to action. This argument is particularly salient in the field of HIV/AIDS prevention. We examined microbicide research and identified challenges that obstruct the integration of clinical trial and behavioral and social science research, thereby reinforcing linear programs of research. We found that behavioral and social science research can both support microbicide clinical trial performance and anticipate the information most needed for a rapid and successful introduction of future microbicide products.

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Year:  2005        PMID: 16317214      PMCID: PMC1470442          DOI: 10.2105/AJPH.2004.043471

Source DB:  PubMed          Journal:  Am J Public Health        ISSN: 0090-0036            Impact factor:   9.308


  21 in total

Review 1.  Acceptability research on female-controlled barrier methods to prevent heterosexual transmission of HIV: Where have we been? Where are we going?

Authors:  C Elias; C Coggins
Journal:  J Womens Health Gend Based Med       Date:  2001-03

2.  HIV prevention research: accomplishments and challenges for the third decade of AIDS.

Authors:  J D Auerbach; T J Coates
Journal:  Am J Public Health       Date:  2000-07       Impact factor: 9.308

3.  The AIDS research model: implications for other infectious diseases of global health importance.

Authors:  G K Folkers; A S Fauci
Journal:  JAMA       Date:  2001-07-25       Impact factor: 56.272

4.  The design of prophylactic trials for HIV: the case of microbicides.

Authors:  Zena A Stein; Landon Myer; Mervyn Susser
Journal:  Epidemiology       Date:  2003-01       Impact factor: 4.822

5.  Why don't we see more translation of health promotion research to practice? Rethinking the efficacy-to-effectiveness transition.

Authors:  Russell E Glasgow; Edward Lichtenstein; Alfred C Marcus
Journal:  Am J Public Health       Date:  2003-08       Impact factor: 9.308

Review 6.  Evaluating patient-based outcome measures for use in clinical trials.

Authors:  R Fitzpatrick; C Davey; M J Buxton; D R Jones
Journal:  Health Technol Assess       Date:  1998       Impact factor: 4.014

Review 7.  Factors affecting the consistent use of barrier methods of contraception.

Authors:  L J Beckman; S M Harvey
Journal:  Obstet Gynecol       Date:  1996-09       Impact factor: 7.661

Review 8.  Faithful but fearful: reducing HIV transmission in stable relationships.

Authors:  I de Zoysa; M D Sweat; J A Denison
Journal:  AIDS       Date:  1996       Impact factor: 4.177

9.  The strategic approach to contraceptive introduction.

Authors:  R Simmons; P Hall; J Díaz; M Díaz; P Fajans; J Satia
Journal:  Stud Fam Plann       Date:  1997-06

10.  Decline in the prevalence of HIV and sexually transmitted diseases among female sex workers in Cotonou, Benin, 1993-1999.

Authors:  Michel Alary; Léonard Mukenge-Tshibaka; France Bernier; Nassirou Geraldo; Catherine M Lowndes; Honoré Meda; Cyriaque A B Gnintoungbè; Séverin Anagonou; Jean R Joly
Journal:  AIDS       Date:  2002-02-15       Impact factor: 4.177

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  24 in total

1.  Assessing microbicide acceptability: a comprehensive and integrated approach.

Authors:  Kathleen M Morrow; Monica S Ruiz
Journal:  AIDS Behav       Date:  2007-06-26

2.  Acceptability of hypothetical microbicides among women in sex establishments in rural areas in Southern China.

Authors:  Yu Wang; Su-Su Liao; Margaret R Weeks; Jing-Mei Jiang; Maryann Abbott; Yue-Jiao Zhou; Bin He; Wei Liu; Katie E Mosack
Journal:  Sex Transm Dis       Date:  2008-01       Impact factor: 2.830

3.  An evaluation of methods to improve the reporting of adherence in a placebo gel trial in Andhra Pradesh, India.

Authors:  Sharon A Abbott; Barbara A Friedland; Avina Sarna; Lauren L Katzen; Ulrike Rawiel; Aylur K Srikrishnan; C S Shalini; Waimar Tun; Christine A Kelly; Suniti Solomon; Barbara S Mensch
Journal:  AIDS Behav       Date:  2013-07

4.  Attitudes towards microbicide use for bacterial vaginosis in pregnancy.

Authors:  Marina Catallozzi; Camille Y Williams; Gregory D Zimet; Katharine M Hargreaves; Shari E Gelber; Adam J Ratner; Lawrence R Stanberry; Susan L Rosenthal
Journal:  Sex Health       Date:  2014-09       Impact factor: 2.706

Review 5.  Candidate hepatitis C vaccine trials and people who inject drugs: challenges and opportunities.

Authors:  Lisa Maher; Bethany White; Margaret Hellard; Annie Madden; Maria Prins; Thomas Kerr; Kimberly Page
Journal:  Vaccine       Date:  2010-09-09       Impact factor: 3.641

6.  Assessing the feasibility of hepatitis C virus vaccine trials: results from the Hepatitis C Incidence and Transmission Study-community (HITS-c) vaccine preparedness study.

Authors:  Bethany White; Annie Madden; Maria Prins; Margaret Hellard; Handan Wand; Gregory J Dore; Kimberly Page; Lisa Maher
Journal:  Vaccine       Date:  2014-08-12       Impact factor: 3.641

7.  Predictors of using a microbicide-like product among adolescent girls.

Authors:  Mary B Short; Paul A Succop; Ana M Ugueto; Susan L Rosenthal
Journal:  J Adolesc Health       Date:  2007-07-20       Impact factor: 5.012

8.  Behavioral and social science research to support development of educational materials for clinical trials of broadly neutralizing antibodies for HIV treatment and prevention.

Authors:  Pablo K Valente; Yumeng Wu; Yehuda Z Cohen; Marina Caskey; Kathrine Meyers
Journal:  Clin Trials       Date:  2020-08-24       Impact factor: 2.486

Review 9.  Research on adolescents and microbicides: a review.

Authors:  Amanda E Tanner; Mary B Short; Gregory D Zimet; Susan L Rosenthal
Journal:  J Pediatr Adolesc Gynecol       Date:  2009-07-17       Impact factor: 1.814

10.  Lessons for Rectal Microbicide Development From an Acceptability Trial of a Placebo Gel Applied Prior to Receptive Anal Intercourse.

Authors:  Timothy Frasca; Rebecca Giguere; Mobolaji Ibitoye; Curtis Dolezal; Irma Febo; Ross D Cranston; Kenneth Mayer; Ian McGowan; Alex Carballo-Diéguez
Journal:  Arch Sex Behav       Date:  2016-04-29
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