| Literature DB >> 16317077 |
A V McDonnell1, T Jiang, A E Keating, B Berger.
Abstract
We introduce Paircoil2, a new version of the Paircoil program, which uses pairwise residue probabilities to detect coiled-coil motifs in protein sequence data. Paircoil2 achieves 98% sensitivity and 97% specificity on known coiled coils in leave-family-out cross-validation. It also shows superior performance compared with published methods in tests on proteins of known structure.Mesh:
Year: 2005 PMID: 16317077 DOI: 10.1093/bioinformatics/bti797
Source DB: PubMed Journal: Bioinformatics ISSN: 1367-4803 Impact factor: 6.937