Literature DB >> 16314138

Evolution of chronic dysphagia following treatment for head and neck cancer.

Nam P Nguyen1, Candace C Moltz, Cheryl Frank, Paul Vos, Herbert J Smith, Ulf Karlsson, Ly M Nguyen, Sue Rose, Suresh Dutta, Sabah Sallah.   

Abstract

We would like to assess the evolution of chronic dysphagia (1 year or more) following treatment for head and neck cancer. Modified barium swallow (MBS) examinations were performed in cancer-free patients who complained of dysphagia following treatment for head and neck cancer. The severity of the dysphagia was graded on a scale of 1-7. Each patient had at least 2 MBS. Severity of dysphagia was compared between the first and last MBS study to determine whether the swallowing dysfunction had returned to normal. Patients with complaint of dysphagia and normal MBS also underwent a regular barium swallow to assess the structural integrity of the pharynx and esophagus. Between 1996 and 2001, 25 patients with dysphagia underwent repeat MBS following treatment. Swallowing dysfunction did not return to normal in the majority of the patients. At a median time of 26 months following treatment (range 15-82 months), only two patient (8%) had normalization of the swallowing. The severity of dysphagia decreased in eight patients (32%), remained unchanged in 12 patients (48%), and worsened in five patients (20%). Eight patients (32%) still had aspiration problems at 12-83 months following treatment. Six patients (24%) required dilation because of pharyngeal stenosis. Three patients who required dilation had improvement of the dysphagia severity. Chronic dysphagia is a relentless process possibly due to excessive scarring. Patients with chronic dysphagia are at risk of malnutrition, and aspiration. Management of chronic dysphagia requires a team approach with nutritional support, psychological counseling, dilation, and tube feedings when indicated.

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Year:  2005        PMID: 16314138     DOI: 10.1016/j.oraloncology.2005.09.003

Source DB:  PubMed          Journal:  Oral Oncol        ISSN: 1368-8375            Impact factor:   5.337


  15 in total

1.  Weight loss and body mass index in relation to aspiration in patients treated for head and neck cancer: a long-term follow-up.

Authors:  Sandra Ottosson; Ulrika Lindblom; Peter Wahlberg; Per Nilsson; Elisabeth Kjellén; Björn Zackrisson; Eva Levring Jäghagen; Göran Laurell
Journal:  Support Care Cancer       Date:  2014-04-01       Impact factor: 3.603

Review 2.  Systematic review of dose--volume correlates for structures related to late swallowing disturbances after radiotherapy for head and neck cancer.

Authors:  Fréderic Duprez; Indira Madani; Bruno De Potter; Tom Boterberg; Wilfried De Neve
Journal:  Dysphagia       Date:  2013-02-22       Impact factor: 3.438

3.  A swallow preservation protocol improves function for veterans receiving chemoradiation for head and neck cancer.

Authors:  Kevin A Peng; Edward C Kuan; Lindsey Unger; William C Lorentz; Marilene B Wang; Jennifer L Long
Journal:  Otolaryngol Head Neck Surg       Date:  2015-03-31       Impact factor: 3.497

4.  Predictors of Patient-Reported Dysphagia Following IMRT Plus Chemotherapy in Oropharyngeal Cancer.

Authors:  Ester Orlandi; Rosalba Miceli; Gabriele Infante; Aurora Mirabile; Daniela Alterio; Maria Cossu Rocca; Nerina Denaro; Riccardo Vigna-Taglianti; Annamaria Merlotti; Antonio Schindler; Nicole Pizzorni; Carlo Fallai; Lisa Licitra; Paolo Bossi
Journal:  Dysphagia       Date:  2018-06-08       Impact factor: 3.438

5.  A prospective investigation of swallowing, nutrition, and patient-rated functional impact following altered fractionation radiotherapy with concomitant boost for oropharyngeal cancer.

Authors:  Bena Cartmill; Petrea Cornwell; Elizabeth Ward; Wendy Davidson; Sandro Porceddu
Journal:  Dysphagia       Date:  2011-02-23       Impact factor: 3.438

Review 6.  Appropriate and necessary oral care for people with cancer: guidance to obtain the right oral and dental care at the right time.

Authors:  Joel B Epstein; Pelin Güneri; Andrei Barasch
Journal:  Support Care Cancer       Date:  2014-03-28       Impact factor: 3.603

7.  Effect of induction chemotherapy on swallow physiology and saliva production in patients with head and neck cancer: a pilot study.

Authors:  Bharat B Mittal; Barbara Roa Pauloski; Alfred W Rademaker; Muveddet Discekici-Harris; Irene B Helenowski; Ann Mellot; Mark Agulnik; Jerilyn A Logemann
Journal:  Head Neck       Date:  2014-04-09       Impact factor: 3.147

8.  Comparison of swallowing function after intensity-modulated radiation therapy and conventional radiotherapy for head and neck cancer.

Authors:  Barbara Roa Pauloski; Alfred W Rademaker; Jerilyn A Logemann; Muveddet Discekici-Harris; Bharat B Mittal
Journal:  Head Neck       Date:  2014-08-01       Impact factor: 3.147

9.  Prospective clinical study on long-term swallowing function and voice quality in advanced head and neck cancer patients treated with concurrent chemoradiotherapy and preventive swallowing exercises.

Authors:  Sophie A C Kraaijenga; Lisette van der Molen; Irene Jacobi; Olga Hamming-Vrieze; Frans J M Hilgers; Michiel W M van den Brekel
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-11-08       Impact factor: 2.503

Review 10.  Dysphagia in head and neck cancer patients treated with chemoradiotherapy.

Authors:  Nele Platteaux; Piet Dirix; Eddy Dejaeger; Sandra Nuyts
Journal:  Dysphagia       Date:  2009-08-27       Impact factor: 3.438

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