PURPOSE: Persistent severe swallowing dysfunction with aspiration is a common and sometimes overlooked sequelae after treatment for squamous cell carcinoma of the head and neck (SCCHN) and may impact food intake and nutritional status. More knowledge is needed to increase the understanding of severe swallowing dysfunction as a risk factor for persistent nutritional deteriorations in SCCHN survivors. The purpose of the study was to investigate weight loss and body mass index (BMI) in relation to pharyngeal swallowing function in a long-term perspective in patients after SCCHN treatment. METHODS: Data from 101 patients were available for the analyses. Swallowing function was assessed by videofluoroscopy at a mean of 71.6 months after the start of radiotherapy (RT). Percent weight change (calculated with weight at the start of RT as the reference) and BMI at follow-up were the primary nutritional measures. RESULTS: Aspiration was present in 48 of 101 patients (48 %). Patients with aspiration had a significantly higher mean weight loss and a lower BMI (-10.9 % and 23.1, respectively) at follow-up compared with patients without aspiration (-2.8 % and 26.0, respectively). Patients with aspiration were unable to gain weight after 23 months. Only ten of 101 patients (10 %) were underweight at follow-up. CONCLUSIONS: Swallowing dysfunction with aspiration was related to long-term weight loss and reduced BMI. Few patients were underweight despite the high prevalence of swallowing dysfunction.
PURPOSE: Persistent severe swallowing dysfunction with aspiration is a common and sometimes overlooked sequelae after treatment for squamous cell carcinoma of the head and neck (SCCHN) and may impact food intake and nutritional status. More knowledge is needed to increase the understanding of severe swallowing dysfunction as a risk factor for persistent nutritional deteriorations in SCCHN survivors. The purpose of the study was to investigate weight loss and body mass index (BMI) in relation to pharyngeal swallowing function in a long-term perspective in patients after SCCHN treatment. METHODS: Data from 101 patients were available for the analyses. Swallowing function was assessed by videofluoroscopy at a mean of 71.6 months after the start of radiotherapy (RT). Percent weight change (calculated with weight at the start of RT as the reference) and BMI at follow-up were the primary nutritional measures. RESULTS: Aspiration was present in 48 of 101 patients (48 %). Patients with aspiration had a significantly higher mean weight loss and a lower BMI (-10.9 % and 23.1, respectively) at follow-up compared with patients without aspiration (-2.8 % and 26.0, respectively). Patients with aspiration were unable to gain weight after 23 months. Only ten of 101 patients (10 %) were underweight at follow-up. CONCLUSIONS:Swallowing dysfunction with aspiration was related to long-term weight loss and reduced BMI. Few patients were underweight despite the high prevalence of swallowing dysfunction.
Authors: Daniel Teitelbaum; Peggi Guenter; Wanda H Howell; Martin E Kochevar; Julie Roth; Douglas L Seidner Journal: Nutr Clin Pract Date: 2005-04 Impact factor: 3.080
Authors: Miriam N Lango; Brian Egleston; Carolyn Fang; Barbara Burtness; Thomas Galloway; Jeffrey Liu; Ranee Mehra; Barbara Ebersole; Kathleen Moran; John A Ridge Journal: Cancer Date: 2013-12-18 Impact factor: 6.860
Authors: Bruce H Campbell; Kristine Spinelli; Anne M Marbella; Katherine B Myers; Joan C Kuhn; Peter M Layde Journal: Arch Otolaryngol Head Neck Surg Date: 2004-09
Authors: Ronald Gavidia; Galit Levi Dunietz; Louise M O'Brien; Sonja G Schütz; Matthew E Spector; Paul L Swiecicki; Ronald D Chervin Journal: J Clin Sleep Med Date: 2022-06-01 Impact factor: 4.324
Authors: B J Heijnen; R Speyer; B Kertscher; R Cordier; K W J Koetsenruijter; K Swan; H Bogaardt Journal: Biomed Res Int Date: 2016-09-19 Impact factor: 3.411
Authors: Uta Lehner; Eugen Zaretsky; Almut Goeze; Laura Wermter; Boris A Stuck; Richard Birk; Andreas Neff; Ingo Fischer; Shahram Ghanaati; Robert Sader; Christiane Hey Journal: HNO Date: 2022-02-04 Impact factor: 1.330
Authors: Sofiana Mootassim-Billah; Gwen Van Nuffelen; Jean Schoentgen; Marc De Bodt; Tatiana Dragan; Antoine Digonnet; Nicolas Roper; Dirk Van Gestel Journal: Cancer Rep (Hoboken) Date: 2021-05-01