Literature DB >> 16313302

Novel polymorphism in the promoter region of the human nerve growth-factor gene.

M Alam1, V Pravica, A A Fryer, C P Hawkins, I V Hutchinson.   

Abstract

We describe a novel T to C transition at position -198 from the transcription start of the human nerve growth-factor (NGF) gene. In British Caucasoid healthy control group that we have genotyped, T and C allele frequencies are 0.633 and 0.367, respectively. This polymorphism affects vitamin D receptor (VDR) binding to its motif in the NGF promoter.

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Year:  2005        PMID: 16313302     DOI: 10.1111/j.1744-313X.2005.00541.x

Source DB:  PubMed          Journal:  Int J Immunogenet        ISSN: 1744-3121            Impact factor:   1.466


  4 in total

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  4 in total

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