Literature DB >> 16309865

In vitro effect of medicinal plants used to treat erectile dysfunction on smooth muscle relaxation and human sperm.

N C Rakuambo1, J J M Meyer, A Hussein, C Huyser, S P Mdlalose, T G Raidani.   

Abstract

Chloroform and ethanol extracts of root bark of Securidaca longepedunculata, Wrightia natalensis and Rhoicissus tridentata were investigated for their in vitro activity on the contraction of corpus cavernosal smooth muscle of white New Zealand rabbits. Some of the extracts of these plants relaxed the corpus cavernosal smooth muscle at low concentrations. The highest activity was obtained from Securidaca longepedunculata chloroform extracts at a concentration of 13.0 mg/ml, which induced 66.6% relaxation. Viagra was used as a positive control in this study. Extracts of Securidaca longepedunculata added to human spermatozoa affected certain sperm parameters negatively at 6.5 mg/ml and higher whilst there was no effect at 1.0 mg/ml.

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Year:  2005        PMID： 16309865     DOI： 10.1016/j.jep.2005.10.008

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  9 in total

1.  Herbal medicines used by Bapedi traditional healers to treat reproductive ailments in the Limpopo Province, South Africa.

Authors:  Ss Semenya; A Maroyi; Mj Potgieter; Ljc Erasmus
Journal:  Afr J Tradit Complement Altern Med       Date:  2012-12-31

Review 2.  Rise of herbal and traditional medicine in erectile dysfunction management.

Authors:  Christopher C K Ho; Hui Meng Tan
Journal:  Curr Urol Rep       Date:  2011-12       Impact factor: 3.092

3.  Evaluation of the sedative and anticonvulsant properties of three Cameroonian plants.

Authors:  Fleur Clarisse Moto Okomolo; Joseph Tanyi Mbafor; Elisabeth Ngo Bum; Nadège Kouemou; Antoine Kavaye Kandeda; Emmanuel Talla; Théophile Dimo; Alice Rakotonirira; Silvère Vincent Rakotonirira
Journal:  Afr J Tradit Complement Altern Med       Date:  2011-07-03

Review 4.  Phytomedicinal therapeutics for male infertility: critical insights and scientific updates.

Authors:  Shalaka S Ramgir; Kaviyarasi Renu; Balachandar Vellingiri; Alex George; Damodaran Tirupapuliyur; Padma Thiagarajan; Abilash Valsala Gopalakrishnan
Journal:  J Nat Med       Date:  2022-04-04       Impact factor: 2.343

5.  Antioxidant, genotoxic and antigenotoxic activities of daphne gnidium leaf extracts.

Authors:  Fadwa Chaabane; Jihed Boubaker; Amira Loussaif; Aicha Neffati; Somaya Kilani-Jaziri; Kamel Ghedira; Leila Chekir-Ghedira
Journal:  BMC Complement Altern Med       Date:  2012-09-13       Impact factor: 3.659

6.  Bapedi traditional healers in the Limpopo Province, South Africa: their socio-cultural profile and traditional healing practice.

Authors:  Sebua S Semenya; Martin J Potgieter
Journal:  J Ethnobiol Ethnomed       Date:  2014-01-10       Impact factor: 2.733

Review 7.  Review of the Traditional Uses, Phytochemistry, and Pharmacological Activities of Rhoicissus Species (Vitaceae).

Authors:  Nondumiso P Dube; Xavier Siwe-Noundou; Rui W M Krause; Douglas Kemboi; Vuyelwa Jacqueline Tembu; Amanda-Lee Manicum
Journal:  Molecules       Date:  2021-04-16       Impact factor: 4.411

Review 8.  A review on plants used for improvement of sexual performance and virility.

Authors:  Nagendra Singh Chauhan; Vikas Sharma; V K Dixit; Mayank Thakur
Journal:  Biomed Res Int       Date:  2014-08-18       Impact factor: 3.411

9.  In vitro and in vivo aphrodisiac properties of the seed extract from Allium tuberosum on corpus cavernosum smooth muscle relaxation and sexual behavior parameters in male Wistar rats.

Authors:  Xingli Tang; Opeyemi J Olatunji; Yifeng Zhou; Xilin Hou
Journal:  BMC Complement Altern Med       Date:  2017-12-01       Impact factor: 3.659
  9 in total

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