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Literature DB >> 16309328

Cytotoxic prenylflavonoids from Artocarpus elasticus.

Horng-Huey Ko¹, Yi-Huang Lu, Sheng-Zehn Yang, Shen-Jeu Won, Chun-Nan Lin.

Abstract

Five new prenylated flavonoids, artelastoheterol (1), artelasticinol (2), cycloartelastoxanthone (3), artelastoxanthone (4), and cycloartelastoxanthendiol (5), along with five known compounds, were isolated from the root bark of Artocarpus elasticus. The structures of 1-5 were elucidated by spectroscopic methods and through comparison with data reported in the literature. The previously known compound artonol A (6) exhibited cytotoxic activity against the A549 human cancer cell line, with an ED50 value of 1.1 microg/mL.

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Year: 2005 PMID： 16309328 DOI： 10.1021/np050287j

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

9 in total

1. Cytotoxic effect of artocarpin on T47D cells.

Authors: Enos Tangke Arung; Britanto Dani Wicaksono; Yohana Ayupriyanti Handoko; Irawan Wijaya Kusuma; Kuniyoshi Shimizu; Dina Yulia; Ferry Sandra
Journal: J Nat Med Date: 2010-06-11 Impact factor: 2.343

2. A new prenylated dihydrochalcone from the leaves of Artocarpus lowii.

Authors: Shajarahtunnur Jamil; Hasnah Mohd Sirat; Ibrahim Jantan; Norio Aimi; Mariko Kitajima
Journal: J Nat Med Date: 2008-02-13 Impact factor: 2.343

3. Cytotoxic and NF-kappaB inhibitory constituents of Artocarpus rigida.

Authors: Yulin Ren; Leonardus B S Kardono; Soedarsono Riswan; Heebyung Chai; Norman R Farnsworth; Djaja D Soejarto; Esperanza J Carcache de Blanco; A Douglas Kinghorn
Journal: J Nat Prod Date: 2010-05-28 Impact factor: 4.050

4. Sepicanin A- A new geranyl flavanone from Artocarpus sepicanus with activity against methicillin-resistant Staphylococcus aureus (MRSA).

Authors: Mohamed M Radwan; Raquel Rodriguez-Guzman; Susan P Manly; Melissa Jacob; Samir A Ross
Journal: Phytochem Lett Date: 2009-05-03 Impact factor: 1.679

5. Anti-Inflammatory Effects of Cycloheterophyllin on Dinitrochlorobenzene-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice.

Authors: Chia-Chen Wang; Chien-Yu Hsiao; Yu-Jou Hsu; Horng-Huey Ko; Der-Chen Chang; Chi-Feng Hung
Journal: Molecules Date: 2022-04-19 Impact factor: 4.927

Cytotoxic prenylflavonoids from Artocarpus elasticus.

1. Cytotoxic effect of artocarpin on T47D cells.

2. A new prenylated dihydrochalcone from the leaves of Artocarpus lowii.

3. Cytotoxic and NF-kappaB inhibitory constituents of Artocarpus rigida.

4. Sepicanin A- A new geranyl flavanone from Artocarpus sepicanus with activity against methicillin-resistant Staphylococcus aureus (MRSA).

5. Anti-Inflammatory Effects of Cycloheterophyllin on Dinitrochlorobenzene-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice.

6. Prenylated Flavonoids from Roots of Glycyrrhiza uralensis Induce Differentiation of B16-F10 Melanoma Cells.

7. Competitive α-glucosidase inhibitors, dihydrobenzoxanthones, from the barks of Artocarpus elasticus.

8. Biosynthesis of silver nanoparticles using Artocarpus elasticus stem bark extract.

Review 9. The Antioxidant Activity of Prenylflavonoids.