Literature DB >> 16307355

Live and deceased donor kidney transplantation in patients aged 75 years and older in the United States.

Jeanne Macrae1, Amy L Friedman, Eli A Friedman, Paul Eggers.   

Abstract

OBJECTIVE: To examine the outcomes of geriatric ESRD patients selected for kidney transplantation.
DESIGN: Data were extracted from the USRDS Standard Analysis Files (SAF). All persons ages 75 and over who received a kidney transplant from 1994 to 2000 were compared with those remaining on dialysis or on a transplant waiting list. Data on mortality or removal from the waiting list were obtained from the United Network for Organ Sharing (UNOS). The main outcome measure was patient and kidney transplant survival.
RESULTS: Superior five year survival after kidney transplantation was attained by the geriatric cohort given a live donor transplant (59.9%), compared with recipients of deceased donor kidneys (40.3%), dialysis patients waiting for transplant (29.7%), and those who were not selected for kidney transplantation and remained on dialysis (12.5%). The likelihood of being removed from the waiting list for any reason was higher in this group (over 75) (30.3%) than in the 66-75 age group (26.8%). Their average annual mortality rate on the waiting list was 7.9, compared to 6.6% for those 66-75.
CONCLUSION: Even after the age of 75 years, kidney transplantation provides substantial life prolongation and excellent graft survival.

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Mesh:

Year:  2005        PMID: 16307355     DOI: 10.1007/s11255-004-0010-6

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN: 0301-1623            Impact factor:   2.266


  14 in total

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Authors:  P Rebollo; F Ortega; J M Baltar; F Alvarez-Ude; R Alvarez Navascués; J Alvarez-Grande
Journal:  Nephrol Dial Transplant       Date:  2001-08       Impact factor: 5.992

2.  The dual kidney transplant registry.

Authors:  E J Alfrey; S M Lerner; A D Lu
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3.  Taking organs from the young to give to the old: is this acceptable?

Authors:  S V Jassal; D A Redelmeier
Journal:  Transplantation       Date:  2002-08-15       Impact factor: 4.939

4.  Renal replacement therapy in elderly patients.

Authors:  P Fauchald; D Albrechtsen; T Leivestad; K J Berg; T Talseth; A Flatmark
Journal:  Transpl Int       Date:  1988-10       Impact factor: 3.782

5.  Kidney transplantation in patients older than 70 years of age.

Authors:  D Albrechtsen; T Leivestad; G Sødal; O Bentdal; K J Berg; I Brekke; P Fauchald; A Flatmark; A Jakobsen; B Lien
Journal:  Transplant Proc       Date:  1995-02       Impact factor: 1.066

6.  Renal transplant recipients over aged 60 have diminished immune activity and a low risk of rejection.

Authors:  Amy L Friedman; Onur Goker; Meredith A Kalish; Giacomo P Basadonna; Alan S Kliger; Margaret J Bia; Marc I Lorber
Journal:  Int Urol Nephrol       Date:  2004       Impact factor: 2.370

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Authors:  Venkateswara K Rao
Journal:  Drugs Aging       Date:  2002       Impact factor: 3.923

8.  Medical decision-making in the last six months of life: choices about limitation of care.

Authors:  T R Fried; M R Gillick
Journal:  J Am Geriatr Soc       Date:  1994-03       Impact factor: 5.562

9.  Kidney transplantation in the elderly: a decision analysis.

Authors:  Sarbjit V Jassal; Murray D Krahn; Gary Naglie; Jeffrey S Zaltzman; Janet M Roscoe; Edward H Cole; Donald A Redelmeier
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10.  The epidemic of aging in renal replacement therapy: an update on elderly patients and their outcomes.

Authors:  K J Jager; P C W van Dijk; F W Dekker; B Stengel; K Simpson; J D Briggs
Journal:  Clin Nephrol       Date:  2003-11       Impact factor: 0.975

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  16 in total

Review 1.  Strategies for an Expanded Use of Kidneys From Elderly Donors.

Authors:  María José Pérez-Sáez; Núria Montero; Dolores Redondo-Pachón; Marta Crespo; Julio Pascual
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Review 2.  Renal transplantation in the elderly.

Authors:  Ramesh Saxena; Xueqing Yu; Mauricio Giraldo; Juan Arenas; Miguel Vazquez; Christopher Y Lu; Nosratola D Vaziri; Fred G Silva; Xin J Zhou
Journal:  Int Urol Nephrol       Date:  2008-11-07       Impact factor: 2.370

Review 3.  [Kidney transplantation in old age].

Authors:  C Kurschat
Journal:  Z Gerontol Geriatr       Date:  2016-07-27       Impact factor: 1.281

Review 4.  Non-medical factors influencing access to renal transplantation.

Authors:  Eszter Panna Vamos; Marta Novak; Istvan Mucsi
Journal:  Int Urol Nephrol       Date:  2009-04-07       Impact factor: 2.370

5.  Managing transplant rejection in the elderly: the benefits of less aggressive immunosuppressive regimens.

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6.  The combined risk of donor quality and recipient age: higher-quality kidneys may not always improve patient and graft survival.

Authors:  Roland A Hernandez; Sayeed K Malek; Edgar L Milford; Samuel R G Finlayson; Stefan G Tullius
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7.  The Effect of Race, Sex, and Insurance Status on Time-to-Listing Decisions for Liver Transplantation.

Authors:  Cindy L Bryce; Chung-Chou Ho Chang; Derek C Angus; Robert M Arnold; Maxwell Farrell; Mark S Roberts
Journal:  J Transplant       Date:  2010-12-23

8.  Comparative survival of elderly renal transplant recipients with a living donor versus a deceased donor: A retrospective single center observational study.

Authors:  Erzsi Tegzess; Antonio W Gomes Neto; Robert A Pol; Silke E de Boer; Hessel Peters-Sengers; Jan-Stephan F Sanders; Stefan P Berger
Journal:  Transpl Int       Date:  2021-10-28       Impact factor: 3.842

9.  Benefit of kidney transplantation beyond 70 years of age.

Authors:  Kristian Heldal; Anders Hartmann; Diana C Grootendorst; Dinanda J de Jager; Torbjørn Leivestad; Aksel Foss; Karsten Midtvedt
Journal:  Nephrol Dial Transplant       Date:  2009-12-27       Impact factor: 5.992

10.  Access to kidney transplantation: outcomes of the non-referred.

Authors:  Meteb M Albugami; Romuald Panek; Steven Soroka; Karthik Tennankore; Bryce A Kiberd
Journal:  Transplant Res       Date:  2012-12-10
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