| Literature DB >> 16304185 |
Francesco Barchiesi1, Elisabetta Spreghini, Alfredo Santinelli, Annette W Fothergill, Stefania Fallani, Esther Manso, Eleonora Pisa, Daniele Giannini, Andrea Novelli, Maria I Cassetta, Teresita Mazzei, Michael G Rinaldi, Giorgio Scalise.
Abstract
We investigated the in vitro and in vivo activities of caspofungin against Aspergillus terreus. The drug increased survival and reduced tissue fungal burden in neutropenic mice. Therefore, our data support the role of caspofungin in treating systemic infections due to this emerging pathogen.Entities:
Mesh:
Substances:
Year: 2005 PMID: 16304185 PMCID: PMC1315968 DOI: 10.1128/AAC.49.12.5133-5135.2005
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191