Literature DB >> 16304142

Prospects for aminoacyl-tRNA synthetase inhibitors as new antimicrobial agents.

Julian Gregston Hurdle1, Alexander John O'Neill, Ian Chopra.   

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Year:  2005        PMID: 16304142      PMCID: PMC1315952          DOI: 10.1128/AAC.49.12.4821-4833.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


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  87 in total

1.  In vitro and in vivo antimalarial activities of a non-glycosidic 18-membered macrolide antibiotic, borrelidin, against drug-resistant strains of Plasmodia.

Authors:  Kazuhiko Otoguro; Hideaki Ui; Aki Ishiyama; Miyuki Kobayashi; Hideaki Togashi; Yoko Takahashi; Rokuro Masuma; Haruo Tanaka; Hiroshi Tomoda; Haruki Yamada; Satoshi Omura
Journal:  J Antibiot (Tokyo)       Date:  2003-08       Impact factor: 2.649

Review 2.  Persistence of antibiotic resistant bacteria.

Authors:  Dan I Andersson
Journal:  Curr Opin Microbiol       Date:  2003-10       Impact factor: 7.934

3.  First report of clinical and microbiological failure in the eradication of glycopeptide-intermediate methicillin-resistant Staphylococcus aureus carriage by mupirocin.

Authors:  J W Decousser; P Pina; J C Ghnassia; J P Bedos; P Y Allouch
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2003-05-08       Impact factor: 3.267

Review 4.  Genetic strategies for antibacterial drug discovery.

Authors:  Lynn Miesel; Jonathan Greene; Todd A Black
Journal:  Nat Rev Genet       Date:  2003-06       Impact factor: 53.242

5.  Isoleucyl-tRNA synthetase mutations in Staphylococcus aureus clinical isolates and in vitro selection of low-level mupirocin-resistant strains.

Authors:  Shigeru Fujimura; Yutaka Tokue; Akira Watanabe
Journal:  Antimicrob Agents Chemother       Date:  2003-10       Impact factor: 5.191

6.  How does Pseudomonas fluorescens avoid suicide from its antibiotic pseudomonic acid?: Evidence for two evolutionarily distinct isoleucyl-tRNA synthetases conferring self-defense.

Authors:  Tatsuo Yanagisawa; Makoto Kawakami
Journal:  J Biol Chem       Date:  2003-04-02       Impact factor: 5.157

7.  Anti-angiogenesis effects of borrelidin are mediated through distinct pathways: threonyl-tRNA synthetase and caspases are independently involved in suppression of proliferation and induction of apoptosis in endothelial cells.

Authors:  Takanori Kawamura; Diana Liu; Murray J Towle; Rena Kageyama; Naoko Tsukahara; Toshiaki Wakabayashi; Bruce A Littlefield
Journal:  J Antibiot (Tokyo)       Date:  2003-08       Impact factor: 2.649

8.  Variable sensitivity to bacterial methionyl-tRNA synthetase inhibitors reveals subpopulations of Streptococcus pneumoniae with two distinct methionyl-tRNA synthetase genes.

Authors:  Daniel R Gentry; Karen A Ingraham; Michael J Stanhope; Stephen Rittenhouse; Richard L Jarvest; Peter J O'Hanlon; James R Brown; David J Holmes
Journal:  Antimicrob Agents Chemother       Date:  2003-06       Impact factor: 5.191

9.  Mupirocin-based decolonization of Staphylococcus aureus carriers in residents of 2 long-term care facilities: a randomized, double-blind, placebo-controlled trial.

Authors:  Lona Mody; Carol A Kauffman; Shelly A McNeil; Andrzej T Galecki; Suzanne F Bradley
Journal:  Clin Infect Dis       Date:  2003-11-06       Impact factor: 9.079

10.  Horizontal transfer of drug-resistant aminoacyl-transfer-RNA synthetases of anthrax and Gram-positive pathogens.

Authors:  James R Brown; Daniel Gentry; Julie A Becker; Karen Ingraham; David J Holmes; Michael J Stanhope
Journal:  EMBO Rep       Date:  2003-07       Impact factor: 8.807

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  72 in total

Review 1.  Adenylating enzymes in Mycobacterium tuberculosis as drug targets.

Authors:  Benjamin P Duckworth; Kathryn M Nelson; Courtney C Aldrich
Journal:  Curr Top Med Chem       Date:  2012       Impact factor: 3.295

2.  IA, database of known ligands of aminoacyl-tRNA synthetases.

Authors:  Mieczyslaw Torchala; Marcin Hoffmann
Journal:  J Comput Aided Mol Des       Date:  2007-09-20       Impact factor: 3.686

3.  A homology model for Clostridium difficile methionyl tRNA synthetase: active site analysis and docking interactions.

Authors:  Ehab Al-Moubarak; Claire Simons
Journal:  J Mol Model       Date:  2010-11-02       Impact factor: 1.810

4.  Enzymatic glycosylation of the topical antibiotic mupirocin.

Authors:  Prakash Parajuli; Ramesh Prasad Pandey; Anaya Raj Pokhrel; Gopal Prasad Ghimire; Jae Kyung Sohng
Journal:  Glycoconj J       Date:  2014-07-30       Impact factor: 2.916

5.  Further characterization of Bacillus subtilis antibiotic biosensors and their use for antibacterial mode-of-action studies.

Authors:  Katherine R Mariner; Nicola Ooi; Deborah Roebuck; Alex J O'Neill; Ian Chopra
Journal:  Antimicrob Agents Chemother       Date:  2011-01-31       Impact factor: 5.191

6.  Garbled messages and corrupted translations.

Authors:  Tilman Schneider-Poetsch; Takeo Usui; Daisuke Kaida; Minoru Yoshida
Journal:  Nat Chem Biol       Date:  2010-03       Impact factor: 15.040

7.  Bacterial resistance to leucyl-tRNA synthetase inhibitor GSK2251052 develops during treatment of complicated urinary tract infections.

Authors:  Karen O'Dwyer; Aaron T Spivak; Karen Ingraham; Sharon Min; David J Holmes; Charles Jakielaszek; Stephen Rittenhouse; Alan L Kwan; George P Livi; Ganesh Sathe; Elizabeth Thomas; Stephanie Van Horn; Linda A Miller; Monique Twynholm; John Tomayko; Marybeth Dalessandro; Madelyn Caltabiano; Nicole E Scangarella-Oman; James R Brown
Journal:  Antimicrob Agents Chemother       Date:  2014-10-27       Impact factor: 5.191

Review 8.  Progress and challenges in aminoacyl-tRNA synthetase-based therapeutics.

Authors:  Christopher S Francklyn; Patrick Mullen
Journal:  J Biol Chem       Date:  2019-01-22       Impact factor: 5.157

9.  Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo.

Authors:  Eva Maria Novoa; Noelia Camacho; Anna Tor; Barrie Wilkinson; Steven Moss; Patricia Marín-García; Isabel G Azcárate; José M Bautista; Adam C Mirando; Christopher S Francklyn; Sònia Varon; Miriam Royo; Alfred Cortés; Lluís Ribas de Pouplana
Journal:  Proc Natl Acad Sci U S A       Date:  2014-12-08       Impact factor: 11.205

10.  Insights into the preclinical treatment of blood-stage malaria by the antibiotic borrelidin.

Authors:  I G Azcárate; P Marín-García; N Camacho; S Pérez-Benavente; A Puyet; A Diez; L Ribas de Pouplana; J M Bautista
Journal:  Br J Pharmacol       Date:  2013-06       Impact factor: 8.739

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