| Literature DB >> 16300906 |
Ze Tian1, Rui Le Pan, Jianyong Si, Pei Gen Xiao.
Abstract
Our previous study had demonstrated cytotoxicity of EtOAc fraction from aerial part of Cimicifuga foetida on various cancer cell lines. In the present study, we investigated the cytotoxicity of five cycloartane triterpenoids isolated from the EtOAc fraction. Compounds (1,2,3) showed moderate cytotoxic activity on R-HepG2 cells and drug resistant sub line R-HepG2 but exhibited less toxicity against primary cultured normal mouse hepatocytes. Compounds (4) and (5) were inactive on all tested cell lines.Entities:
Mesh：
Substances：
Year: 2005 PMID： 16300906 DOI： 10.1016/j.fitote.2005.08.001
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882