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Literature DB >> 16298816

Notch signaling in hematopoietic stem cells.

Abstract

The molecular basis of the hematopoietic stem cell (HSC) "niche" has gradually been elucidated. This new knowledge may help us understand how the self-renewal of HSCs is physiologically regulated and may give us clues for developing methods for ex vivo HSC expansion. The Notch pathway is an environmental signaling system that may play an important role in the HSC niche. In this review, we focus on the role of Notch signaling in the regulation of hematopoietic stem and progenitor cells in both embryo and adult hematopoiesis and clarify what is known regarding the self-renewal of HSCs.

Entities: Disease

Mesh：

Substances：
Receptors, Notch

Year: 2005 PMID： 16298816 DOI： 10.1532/IJH97.05115

Source DB: PubMed Journal: Int J Hematol ISSN： 0925-5710 Impact factor: 2.490

108 in total

Review 1. An overview of the Notch signalling pathway.

Authors: Martin Baron
Journal: Semin Cell Dev Biol Date: 2003-04 Impact factor: 7.727

2. Soluble Jagged-1 is able to inhibit the function of its multivalent form to induce hematopoietic stem cell self-renewal in a surrogate in vitro assay.

Authors: Virág Vas; László Szilágyi; Katalin Pálóczi; Ferenc Uher
Journal: J Leukoc Biol Date: 2004-01-23 Impact factor: 4.962

3. RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

Authors: Alex Robert-Moreno; Lluís Espinosa; José Luis de la Pompa; Anna Bigas
Journal: Development Date: 2005-02-02 Impact factor: 6.868

4. Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation.

Authors: G Bhardwaj; B Murdoch; D Wu; D P Baker; K P Williams; K Chadwick; L E Ling; F N Karanu; M Bhatia
Journal: Nat Immunol Date: 2001-02 Impact factor: 25.606

Review 5. Notch signaling in the integrated control of keratinocyte growth/differentiation and tumor suppression.

Authors: Karine Lefort; G Paolo Dotto
Journal: Semin Cancer Biol Date: 2004-10 Impact factor: 15.707

6. VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism.

Authors: Hans-Peter Gerber; Ajay K Malik; Gregg P Solar; Daniel Sherman; Xiao Huan Liang; Gloria Meng; Kyu Hong; James C Marsters; Napoleone Ferrara
Journal: Nature Date: 2002-06-27 Impact factor: 49.962

7. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis.

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Journal: Cell Date: 1996-01-26 Impact factor: 41.582

8. Development of hematopoietic stem cell activity in the mouse embryo.

Authors: A M Müller; A Medvinsky; J Strouboulis; F Grosveld; E Dzierzak
Journal: Immunity Date: 1994-07 Impact factor: 31.745

9. Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila.

Authors: X Sun; S Artavanis-Tsakonas
Journal: Development Date: 1997-09 Impact factor: 6.868

10. Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice.

Authors: D Bellavia; A F Campese; E Alesse; A Vacca; M P Felli; A Balestri; A Stoppacciaro; C Tiveron; L Tatangelo; M Giovarelli; C Gaetano; L Ruco; E S Hoffman; A C Hayday; U Lendahl; L Frati; A Gulino; I Screpanti
Journal: EMBO J Date: 2000-07-03 Impact factor: 11.598

16 in total

Review 1. Molecular mediators of mesenchymal stem cell biology.

Authors: Maria P Alfaro; Sarika Saraswati; Pampee P Young
Journal: Vitam Horm Date: 2011 Impact factor: 3.421

2. Stem Cells in Aging: Influence of Ontogenic, Genetic and Environmental Factors.

Authors: Edmond J Yunis; Joaquin Zúñiga; Prasad S Koka; Zaheed Husain; Viviana Romero; Joel N H Stern; Masha Fridkis-Hareli
Journal: J Stem Cells Date: 2006

3. Notch1 expression is regulated at the post-transcriptional level by the 3' untranslated region in hematopoietic stem cell development.

Authors: Shinichi Mizuno; Tadafumi Iino; Hidetoshi Ozawa; Yojiro Arinobu; Yong Chong; Koichi Akashi
Journal: Int J Hematol Date: 2017-11-02 Impact factor: 2.490

4. Hes1 suppresses acute myeloid leukemia development through FLT3 repression.

Authors: T Kato; M Sakata-Yanagimoto; H Nishikii; M Ueno; Y Miyake; Y Yokoyama; Y Asabe; Y Kamada; H Muto; N Obara; K Suzukawa; Y Hasegawa; I Kitabayashi; K Uchida; A Hirao; H Yagita; R Kageyama; S Chiba
Journal: Leukemia Date: 2014-09-19 Impact factor: 11.528

5. sFRP2 suppression of bone morphogenic protein (BMP) and Wnt signaling mediates mesenchymal stem cell (MSC) self-renewal promoting engraftment and myocardial repair.

Authors: Maria P Alfaro; Alicia Vincent; Sarika Saraswati; Curtis A Thorne; Charles C Hong; Ethan Lee; Pampee P Young
Journal: J Biol Chem Date: 2010-09-07 Impact factor: 5.157

6. Evolution of the chordate regeneration blastema: Differential gene expression and conserved role of notch signaling during siphon regeneration in the ascidian Ciona.

Authors: Mayuko Hamada; Spela Goricki; Mardi S Byerly; Noriyuki Satoh; William R Jeffery
Journal: Dev Biol Date: 2015-07-20 Impact factor: 3.582

7. Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge.

Authors: Sailay Siddiqi; Natalie Gude; Toru Hosoda; John Muraski; Marta Rubio; Gregory Emmanuel; Jenna Fransioli; Serena Vitale; Carola Parolin; Domenico D'Amario; Erik Schaefer; Jan Kajstura; Annarosa Leri; Piero Anversa; Mark A Sussman
Journal: Circ Res Date: 2008-06-02 Impact factor: 17.367