Literature DB >> 16298002

The impact of introducing intensity modulated radiotherapy into routine clinical practice.

Elizabeth A Miles1, Catharine H Clark, M Teresa Guerrero Urbano, Margaret Bidmead, David P Dearnaley, Kevin J Harrington, Roger A'Hern, Christopher M Nutting.   

Abstract

BACKGROUND AND
PURPOSE: Intensity modulated radiotherapy (IMRT) at the Royal Marsden Hospital London was introduced in July 2001. Treatment delivery was dynamic using a single-phase technique. Concerns were raised regarding increased clinical workload due to introduction of new technology. The potential increased use of resources was assessed. PATIENTS AND METHODS: IMRT patient selection was within guidelines of clinical trials and included patients undergoing prostate plus pelvic lymph node (PPN) irradiation and head and neck cancer (HNC) treatment. Patient planning, quality assurance and treatment times were collected for an initial IMRT patient group. A comparative group of patients with advanced HNC undergoing two- or three-phase conventional radiotherapy, requiring matched photon and electron fields, were also timed.
RESULTS: The median overall total planning time for IMRT was greater for HNC patients compared to the PPN cohort. For HNC the overall IMRT planning time was significantly longer than for conventional. The median treatment time for conventional two- or three-phase HNC treatments, encompassing similar volumes to those treated with IMRT, was greater than that for the IMRT HNC patient cohort. A reduction in radiographer man hours per patient of 4.8h was recorded whereas physics time was increased by 4.9h per patient.
CONCLUSIONS: IMRT currently increases overall planning time. Additional clinician input is required for target volume localisation. Physics time is increased, a significant component of this being patient specific QA. Radiographer time is decreased. For HNC a single phase IMRT treatment has proven to be more efficient than a multiple phase conventional treatment. IMRT has been integrated smoothly and efficiently into the existing treatment working day. This preliminary study suggests that IMRT could be a routine treatment with efficient use of current radiotherapy resources.

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Mesh:

Year:  2005        PMID: 16298002     DOI: 10.1016/j.radonc.2005.10.011

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  27 in total

Review 1.  Volumetric modulated arc therapy: a review of current literature and clinical use in practice.

Authors:  M Teoh; C H Clark; K Wood; S Whitaker; A Nisbet
Journal:  Br J Radiol       Date:  2011-11       Impact factor: 3.039

2.  IMRT and IGRT in head and neck cancer: Have we delivered what we promised?

Authors:  Gupta Tejpal; Agarwal Jaiprakash; Bannerjee Susovan; Sarbani Ghosh-Laskar; Vedang Murthy; Ashwini Budrukkar
Journal:  Indian J Surg Oncol       Date:  2010-11-21

3.  Late toxicity, evolving radiotherapy techniques, and quality of life in nasopharyngeal carcinoma.

Authors:  Luciana Lastrucci; Silvia Bertocci; Vittorio Bini; Simona Borghesi; Roberta De Majo; Andrea Rampini; Paola Pernici; Pietro Giovanni Gennari
Journal:  Radiol Med       Date:  2017-01-09       Impact factor: 3.469

4.  Estimating the costs of intensity-modulated and 3-dimensional conformal radiotherapy in Ontario.

Authors:  J H E Yong; T McGowan; R Redmond-Misner; J Beca; P Warde; E Gutierrez; J S Hoch
Journal:  Curr Oncol       Date:  2016-06-09       Impact factor: 3.677

Review 5.  Cost-effectiveness landscape analysis of treatments addressing xerostomia in patients receiving head and neck radiation therapy.

Authors:  Laura S Sasportas; Drew N Hosford; Maria A Sodini; Dale J Waters; Elizabeth A Zambricki; Joëlle K Barral; Edward E Graves; Todd J Brinton; Paul G Yock; Quynh-Thu Le; Davud Sirjani
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol       Date:  2013-05-03

6.  [Prediction of three-dimensional dose distribution in intensity-modulated radiation therapy based on neural network learning].

Authors:  Fan-Tu Kong; Yan-Hua Mai; Meng-Ke Qi; Ai-Qian Wu; Fu-Tong Guo; Qi-Yuan Jia; Yong-Bao Li; Ting Song; Ling-Hong Zhou
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2018-06-20

7.  "What goes round comes round".

Authors:  Bjj Abdullah
Journal:  Biomed Imaging Interv J       Date:  2006-01-01

8.  Conformal radiotherapy and molecular imaging: complementary technologies in cancer therapy.

Authors:  Mp Mac Manus
Journal:  Biomed Imaging Interv J       Date:  2006-01-01

Review 9.  Dosimetric comparison of intensity modulated radiotherapy and three-dimensional conformal radiotherapy in patients with gynecologic malignancies: a systematic review and meta-analysis.

Authors:  Baojuan Yang; Lin Zhu; Haiyan Cheng; Qi Li; Yunyan Zhang; Yashuang Zhao
Journal:  Radiat Oncol       Date:  2012-11-23       Impact factor: 3.481

10.  Survival benefit of adding chemotherapy to intensity modulated radiation in patients with locoregionally advanced nasopharyngeal carcinoma.

Authors:  Xuemei Ji; Conghua Xie; Desheng Hu; Xia Fan; Yajuan Zhou; Yingjie Zheng
Journal:  PLoS One       Date:  2013-02-18       Impact factor: 3.240

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