Literature DB >> 27330359

Estimating the costs of intensity-modulated and 3-dimensional conformal radiotherapy in Ontario.

J H E Yong1, T McGowan2, R Redmond-Misner1, J Beca1, P Warde3, E Gutierrez4, J S Hoch5.   

Abstract

BACKGROUND: Radiotherapy is a common treatment for many cancers, but up-to-date estimates of the costs of radiotherapy are lacking. In the present study, we estimated the unit costs of intensity-modulated radiotherapy (imrt) and 3-dimensional conformal radiotherapy (3D-crt) in Ontario.
METHODS: An activity-based costing model was developed to estimate the costs of imrt and 3D-crt in prostate cancer. It included the costs of equipment, staff, and supporting infrastructure. The framework was subsequently adapted to estimate the costs of radiotherapy in breast cancer and head-and-neck cancer. We also tested various scenarios by varying the program maturity and the use of volumetric modulated arc therapy (vmat) alongside imrt.
RESULTS: From the perspective of the health care system, treating prostate cancer with imrt and 3D-crt respectively cost $12,834 and $12,453 per patient. The cost of radiotherapy ranged from $5,270 to $14,155 and was sensitive to analytic perspective, radiation technique, and disease site. Cases of head-and-neck cancer were the most costly, being driven by treatment complexity and fractions per treatment. Although imrt was more costly than 3D-crt, its cost will likely decline over time as programs mature and vmat is incorporated.
CONCLUSIONS: Our costing model can be modified to estimate the costs of 3D-crt and imrt for various disease sites and settings. The results demonstrate the important role of capital costs in studies of radiotherapy cost from a health system perspective, which our model can accommodate. In addition, our study established the need for future analyses of imrt cost to consider how vmat affects time consumption.

Entities:  

Keywords:  Radiotherapy; breast neoplasms; cost analyses; costs; head-and-neck neoplasms; intensity-modulated radiotherapy; prostate neoplasms

Year:  2016        PMID: 27330359      PMCID: PMC4900842          DOI: 10.3747/co.23.2998

Source DB:  PubMed          Journal:  Curr Oncol        ISSN: 1198-0052            Impact factor:   3.677


  28 in total

1.  The cost of radiotherapy as a function of facility size and hours of operation.

Authors:  P Dunscombe; G Roberts; J Walker
Journal:  Br J Radiol       Date:  1999-06       Impact factor: 3.039

Review 2.  The cost of radiation therapy.

Authors:  Nicolas Paul Ploquin; Peter Brian Dunscombe
Journal:  Radiother Oncol       Date:  2008-01-30       Impact factor: 6.280

3.  Measuring the cost of palliative radiotherapy.

Authors:  P Warde; T Murphy
Journal:  Can J Oncol       Date:  1996-02

Review 4.  Systematic review of the cost effectiveness of radiation therapy for prostate cancer from 2003 to 2013.

Authors:  Neha P Amin; David J Sher; Andre A Konski
Journal:  Appl Health Econ Health Policy       Date:  2014-08       Impact factor: 2.561

5.  Toxicity and cost-effectiveness analysis of intensity modulated radiation therapy versus 3-dimensional conformal radiation therapy for postoperative treatment of gynecologic cancers.

Authors:  L Andy Chen; Jaewhan Kim; Kenneth Boucher; Breanne Terakedis; Britney Williams; Nancy A Nickman; David K Gaffney
Journal:  Gynecol Oncol       Date:  2015-01-03       Impact factor: 5.482

6.  A multicentre timing study of intensity-modulated radiotherapy planning and delivery.

Authors:  S J Thomas; A Vinall; A Poynter; D Routsis
Journal:  Clin Oncol (R Coll Radiol)       Date:  2010-10       Impact factor: 4.126

7.  Cost-effectiveness analysis of intensity modulated radiation therapy versus 3-dimensional conformal radiation therapy for anal cancer.

Authors:  Joseph C Hodges; Muhammad S Beg; Prajnan Das; Jeffrey Meyer
Journal:  Int J Radiat Oncol Biol Phys       Date:  2014-04-09       Impact factor: 7.038

8.  Incidence of late rectal and urinary toxicities after three-dimensional conformal radiotherapy and intensity-modulated radiotherapy for localized prostate cancer.

Authors:  Michael J Zelefsky; Emily J Levin; Margie Hunt; Yoshiya Yamada; Alison M Shippy; Andrew Jackson; Howard I Amols
Journal:  Int J Radiat Oncol Biol Phys       Date:  2008-03-15       Impact factor: 7.038

9.  Two-year and lifetime cost-effectiveness of intensity modulated radiation therapy versus 3-dimensional conformal radiation therapy for head-and-neck cancer.

Authors:  Racquel E Kohler; Nathan C Sheets; Stephanie B Wheeler; Chris Nutting; Emma Hall; Bhishamjit S Chera
Journal:  Int J Radiat Oncol Biol Phys       Date:  2013-11-15       Impact factor: 7.038

10.  Volumetric modulated arc therapy is superior to conventional intensity modulated radiotherapy--a comparison among prostate cancer patients treated in an Australian centre.

Authors:  Gerald B Fogarty; Diana Ng; Guilin Liu; Lauren E Haydu; Nastik Bhandari
Journal:  Radiat Oncol       Date:  2011-09-05       Impact factor: 3.481

View more
  9 in total

Review 1.  Cost of New Technologies in Prostate Cancer Treatment: Systematic Review of Costs and Cost Effectiveness of Robotic-assisted Laparoscopic Prostatectomy, Intensity-modulated Radiotherapy, and Proton Beam Therapy.

Authors:  Florian Rudolf Schroeck; Bruce L Jacobs; Sam B Bhayani; Paul L Nguyen; David Penson; Jim Hu
Journal:  Eur Urol       Date:  2017-03-31       Impact factor: 20.096

2.  Real-world costing analysis for diffuse large B-cell lymphoma in British Columbia.

Authors:  S Costa; D W Scott; C Steidl; S J Peacock; D A Regier
Journal:  Curr Oncol       Date:  2019-04-01       Impact factor: 3.677

3.  Proton Beam Therapy for Cancer in Children and Adults: A Health Technology Assessment.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2021-05-06

4.  History and Current State of Radiation Oncology Services and Practice in Jordan.

Authors:  Jamal Khader; Abdelatif Al Mousa; Samir Al-Kayed; Hana Mahasneh; Rasmi Mubaidin; Nabeel Al Nassir; Sami Khatib; Adnan Qasem; Inad Haddadin; Elayan Elayan; Sondos Al Khatib
Journal:  JCO Glob Oncol       Date:  2020-06

5.  Cost Analysis of Selected Radiotherapeutic Modalities for Prostate Cancer Treatment-Czech Republic Case Study for the Purposes of Hospital Based HTA.

Authors:  Petra Hospodková; Tomáš Husár; Barbora Klíčová; Lucie Severová; Karel Šrédl; Roman Svoboda
Journal:  Healthcare (Basel)       Date:  2021-01-19

6.  Economic Evaluation of a Geriatric Oncology Clinic.

Authors:  Shabbir M H Alibhai; Zuhair Alam; Ronak Saluja; Uzair Malik; Padraig Warde; Rana Jin; Arielle Berger; Lindy Romanovsky; Kelvin K W Chan
Journal:  Cancers (Basel)       Date:  2022-02-03       Impact factor: 6.639

7.  PET-Based Staging Is Cost-Effective in Early-Stage Follicular Lymphoma.

Authors:  Andrea C Lo; Lyndon P James; Anca Prica; Adam Raymakers; Stuart Peacock; Melody Qu; Alex V Louie; Kerry J Savage; Laurie H Sehn; David Hodgson; Joanna C Yang; Hans T T Eich; Andrew Wirth; M G Myriam Hunink
Journal:  J Nucl Med       Date:  2021-08-19       Impact factor: 10.057

8.  Local surgical complication rates in patients receiving surgery without immediate post-operative radiation therapy for lower extremity bone metastases.

Authors:  William Pidduck; Leah Drost; Albert Yee; Edward Chow; Ravi Tuazon; Patrick Henry
Journal:  J Bone Oncol       Date:  2020-04-23       Impact factor: 4.072

9.  The challenge of sustainability in healthcare systems: cost of radiotherapy in the last month of life in an Italian cancer center.

Authors:  Romina Rossi; Valentina Danesi; Ilaria Massa; William Balzi; Antonino Romeo; Flavia Foca; Oriana Nanni; Marco Maltoni; Mattia Altini
Journal:  Support Care Cancer       Date:  2020-09-28       Impact factor: 3.603

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.