Catalytic and enantioselective allylic C-H activation with donor-acceptor-substituted carbenoids.

In this perspective we give an overview of enantioselective C-H activation at allylic sites by means of rhodium(II)-stabilized donor-acceptor-substituted carbenoids. This methodology has been proven to be both an equivalent to established asymmetric reaction sequences and a new synthetic approach with no established counterpart in organic synthesis.