Literature DB >> 1629017

Incorporation of radioiodinated IPPA and BMIPP fatty acid analogues into complex lipids from isolated rat hearts.

J Kropp1, K R Ambrose, F F Knapp, H P Nissen, H J Biersack.   

Abstract

Heart lipids were extracted by the Folch technique from Langendorff-perfused rat hearts after administration of 15-(p-[131I]iodophenyl)pentadecanoic acid and 15-(p-[125I]iodophenyl)-3-R,S-methylpentadecanoic acid. Techniques utilizing successive high performance liquid chromatographic (HPLC) analyses have been developed for the evaluation of the uptake of the tracers into neutral lipids and phospholipids of the rat hearts. Phospholipids were separated on a SiO2 column eluted with a gradient of acetonitrile/water (97.5/2.5) and acetonitrile/water (85/15) followed by separation of the neutral lipids on a C-18 reversed phase column with a gradient consisting of acetonitrile and 2-propanol/hexane (60/40) containing 1 N H2SO4 (5 microL/100 mL). Both tracers show the incorporation into the expected major lipid classes.

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Year:  1992        PMID： 1629017     DOI： 10.1016/0883-2897(92)90112-c

Source DB:  PubMed          Journal:  Int J Rad Appl Instrum B        ISSN： 0883-2897


  8 in total

Review 1.  BMIPP-design and development.

Authors:  F F Knapp; J Kropp
Journal:  Int J Card Imaging       Date:  1999-02

Review 2.  Iodine-123-labelled fatty acids for myocardial single-photon emission tomography: current status and future perspectives.

Authors:  F F Knapp; J Kropp
Journal:  Eur J Nucl Med       Date:  1995-04

3.  Combined thallium-201 and dynamic iodine-123 iodophenylpentadecanoic acid single-photon emission computed tomography in patients after acute myocardial infarction with effective reperfusion.

Authors:  W S Richter; S Beckmann; M Cordes; T Schuppenhauer; M Schartl; D L Munz
Journal:  Clin Cardiol       Date:  2000-12       Impact factor: 2.882

4.  Evaluation of pancreatic lipase activity by simple urine analysis after oral administration of a new iodine-131-labeled triglyceride.

Authors:  J Kropp; F F Knapp; A Weyenberg; D W McPherson; K R Ambrose; A P Callahan; K von Bergmann; H J Biersack
Journal:  Eur J Nucl Med       Date:  1994-11

5.  Long chain fatty acid uptake in vivo: comparison of [125I]-BMIPP and [3H]-bromopalmitate.

Authors:  Jane Shearer; Kimberly R Coenen; R Richard Pencek; Larry L Swift; David H Wasserman; Jeffrey N Rottman
Journal:  Lipids       Date:  2008-05-15       Impact factor: 1.880

6.  Incorporation of radioiodinated fatty acids into cardiac phospholipids of normoxic canine myocardium.

Authors:  G W Sloof; F C Visser; T Teerlink; E F Comans; M J Eenige van; G J van der Vusse; F F Knapp
Journal:  Mol Cell Biochem       Date:  1992-10-21       Impact factor: 3.396

7.  Myocardial dysfunction and depressed fatty acid metabolism in patients with cyanotic congenital heart disease.

Authors:  C Kondo; M Nakazawa; K Kusakabe; K Momma
Journal:  J Nucl Cardiol       Date:  1996 Jan-Feb       Impact factor: 5.952

8.  Kinetics of radioiodinated species in subcellular fractions from rat hearts following administration of iodine-123-labelled 15-(p-iodophenyl)-3-(R,S)-methylpentadecanoic acid (123I-BMIPP).

Authors:  S Morishita; H Kusuoka; Y Yamamichi; N Suzuki; M Kurami; T Nishimura
Journal:  Eur J Nucl Med       Date:  1996-04
  8 in total

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