Literature DB >> 16286462

Pathways to the diagnosis of colorectal cancer: an observational study in three UK cities.

Jacqueline Barrett1, Moyez Jiwa, Peter Rose, William Hamilton.   

Abstract

BACKGROUND: Colorectal cancer can present in a variety of ways, and with any of several symptoms. Different referral routes from primary to secondary care cater for these different presentations. The route that has received most investment in the UK National Health Service is the 2-week clinic, but the proportions of patients taking this and other routes to diagnosis are largely unknown.
METHODS: We designed an observational audit in Exeter, Oxford and Sheffield, UK. Colorectal cancers diagnosed in 2002 from participating practices were identified and the presence and timing of seven important clinical features noted: diarrhoea, constipation, rectal bleeding, abdominal pain, the finding of an abdominal or rectal mass on examination, anaemia and positive faecal occult blood tests. The referral pathways to secondary care were identified.
RESULTS: Of the 151 patients studied, 112 (74%) were referred with at least one clinical feature of colorectal cancer to a specialist. Only 43 of these (28% of the total) were referred to a 2-week clinic; 39 patients (26% of the total) had an emergency admission, of whom 10 (7%) had their emergency admission after referral to a specialist for investigation but before a diagnosis had been established. The time intervals between the first consultation with a symptom of cancer and referral were mostly short.
CONCLUSION: Patients with colorectal cancer travel several different pathways to diagnosis. The pathway with the most resources-the 2-week clinic-is used by a minority of patients.

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Year:  2005        PMID: 16286462     DOI: 10.1093/fampra/cmi093

Source DB:  PubMed          Journal:  Fam Pract        ISSN: 0263-2136            Impact factor:   2.267


  29 in total

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2.  Diagnosis Setting and Colorectal Cancer Outcomes: The Impact of Cancer Diagnosis in the Emergency Department.

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4.  How sharp can a screening tool be? A qualitative study of patients' experience of completing a bowel cancer screening questionnaire.

Authors:  Wendy Pugh; Alison M Porter
Journal:  Health Expect       Date:  2010-09-23       Impact factor: 3.377

Review 5.  Role of Raman spectroscopy and surface enhanced Raman spectroscopy in colorectal cancer.

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6.  Primary-to-secondary care referral experience of suspected colorectal malignancy in young adults.

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7.  Delays in referral from primary care worsen survival for patients with colorectal cancer: a retrospective cohort study.

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Journal:  Br J Gen Pract       Date:  2020-06-25       Impact factor: 5.386

8.  Five misconceptions in cancer diagnosis.

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9.  The CAPER studies: five case-control studies aimed at identifying and quantifying the risk of cancer in symptomatic primary care patients.

Authors:  W Hamilton
Journal:  Br J Cancer       Date:  2009-12-03       Impact factor: 7.640

Review 10.  Diagnostic accuracy systematic review of rectal bleeding in combination with other symptoms, signs and tests in relation to colorectal cancer.

Authors:  M Olde Bekkink; C McCowan; G A Falk; C Teljeur; F A Van de Laar; T Fahey
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