BACKGROUND: Our aim was to investigate quality of life and outcome after microvascular free-flap reconstruction after oncologic surgery. METHODS: Forty-four patients with a large carcinoma in the oral cavity, oral pharynx, or hypopharynx underwent free-flap surgery with or without radiotherapy. Patients completed the University of Washington Quality-of-Life Questionnaire preoperatively and four times during the 12 postoperative months. Survival rates and complications were analyzed. RESULTS: Postoperative composite quality-of-life scores were significantly lower than before treatment with no significant overall improvement during the follow-up. The scores for disfigurement, chewing, speech, and shoulder function remained significantly below the preoperative level throughout the follow-up. Sociodemographic factors predicted quality of life. Heavy drinking and unemployment caused a 2.4-fold and a 4.4-fold increase in risk of death, respectively. The rates for overall survival, tumor recurrence, flap success, and surgical complications were consistent with previous literature. CONCLUSION: Sociodemographic variables affect quality of life and patient survival in patients with oral cancer treated with microvascular free-flap reconstruction. (c) 2005 Wiley Periodicals, Inc.
BACKGROUND: Our aim was to investigate quality of life and outcome after microvascular free-flap reconstruction after oncologic surgery. METHODS: Forty-four patients with a large carcinoma in the oral cavity, oral pharynx, or hypopharynx underwent free-flap surgery with or without radiotherapy. Patients completed the University of Washington Quality-of-Life Questionnaire preoperatively and four times during the 12 postoperative months. Survival rates and complications were analyzed. RESULTS: Postoperative composite quality-of-life scores were significantly lower than before treatment with no significant overall improvement during the follow-up. The scores for disfigurement, chewing, speech, and shoulder function remained significantly below the preoperative level throughout the follow-up. Sociodemographic factors predicted quality of life. Heavy drinking and unemployment caused a 2.4-fold and a 4.4-fold increase in risk of death, respectively. The rates for overall survival, tumor recurrence, flap success, and surgical complications were consistent with previous literature. CONCLUSION: Sociodemographic variables affect quality of life and patient survival in patients with oral cancer treated with microvascular free-flap reconstruction. (c) 2005 Wiley Periodicals, Inc.
Authors: Wess A Cohen; Claudia R Albornoz; Peter G Cordeiro; Jennifer Cracchiolo; Elizabeth Encarnacion; Meghan Lee; Michele Cavalli; Snehal Patel; Andrea L Pusic; Evan Matros Journal: Plast Reconstr Surg Date: 2016-12 Impact factor: 4.730
Authors: Benedicta E Beck-Broichsitter; Jörn Huck; Thomas Küchler; Daniela Hauke; Jürgen Hedderich; Jörg Wiltfang; Stephan T Becker Journal: J Cancer Res Clin Oncol Date: 2016-10-18 Impact factor: 4.553
Authors: Thales Salles Angelim Viana; Paulo Goberlânio de Barros Silva; Karuza Maria Alves Pereira; Mario Rogério Lima Mota; Ana Paula Negreiros Nunes Alves; Eric Fernandes de Souza; Fabricio Bitu Sousa Journal: Asian Pac J Cancer Prev Date: 2017-08-27
Authors: J K Meier; J G Schuderer; F Zeman; Ch Klingelhöffer; M Hullmann; G Spanier; T E Reichert; T Ettl Journal: BMC Oral Health Date: 2019-04-27 Impact factor: 2.757