Literature DB >> 16282290

Prevalence of Plasmodium falciparum mutations associated with antimalarial drug resistance during an epidemic in Kuna Yala, Panama, Central America.

Franklyn Samudio1, Ana M Santamaría, Nicanor Obaldía, Juan M Pascale, Vicente Bayard, Jose E Calzada.   

Abstract

A molecular epidemiology study was conducted to determine the distribution of antimalarial drug resistance alleles among field isolates of Plasmodium falciparum. Samples were obtained during an epidemic affecting Kuna Amerindians in Panama. A high prevalence of mutations associated with chloroquine, pyrimethamine, and sulfadoxine was observed. Genotype analysis of msp2 revealed a low genetic diversity of P. falciparum parasites circulating in the studied area. The public health implications of these findings for the Central American region are discussed.

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Year:  2005        PMID： 16282290

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  16 in total

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Authors:  Thiago R Morais; Paulete Romoff; Oriana A Fávero; Juliana Q Reimão; Walkyria C Lourenço; André G Tempone; Angelica D Hristov; Silvia M Di Santi; João Henrique G Lago; Patricia Sartorelli; Marcelo J P Ferreira
Journal:  Parasitol Res       Date:  2011-05-26       Impact factor: 2.289

2.  Molecular analysis of chloroquine and sulfadoxine-pyrimethamine resistance-associated alleles in Plasmodium falciparum isolates from Nicaragua.

Authors:  Sankar Sridaran; Betzabe Rodriguez; Aida Mercedes Soto; Alexandre Macedo De Oliveira; Venkatachalam Udhayakumar
Journal:  Am J Trop Med Hyg       Date:  2014-03-10       Impact factor: 2.345

3.  Malaria in selected non-Amazonian countries of Latin America.

Authors:  Myriam Arevalo-Herrera; Martha Lucia Quiñones; Carlos Guerra; Nora Céspedes; Sandra Giron; Martha Ahumada; Juan Gabriel Piñeros; Norma Padilla; Zilka Terrientes; Angel Rosas; Julio Cesar Padilla; Ananias A Escalante; John C Beier; Socrates Herrera
Journal:  Acta Trop       Date:  2011-07-01       Impact factor: 3.112

4.  Clonal outbreak of Plasmodium falciparum infection in eastern Panama.

Authors:  Nicanor Obaldia; Nicholas K Baro; Jose E Calzada; Ana M Santamaria; Rachel Daniels; Wesley Wong; Hsiao-Han Chang; Elizabeth J Hamilton; Myriam Arevalo-Herrera; Socrates Herrera; Dyann F Wirth; Daniel L Hartl; Matthias Marti; Sarah K Volkman
Journal:  J Infect Dis       Date:  2014-10-21       Impact factor: 5.226

5.  Efficacy of chloroquine for the treatment of uncomplicated Plasmodium falciparum malaria in Honduras.

Authors:  Rosa Elena Mejia Torres; Engels Ilich Banegas; Meisy Mendoza; Cesar Diaz; Sandra Tamara Mancero Bucheli; Gustavo A Fontecha; Md Tauqeer Alam; Ira Goldman; Venkatachalam Udhayakumar; Jose Orlinder Nicolas Zambrano
Journal:  Am J Trop Med Hyg       Date:  2013-03-04       Impact factor: 2.345

6.  Species composition and distribution of adult Anopheles (Diptera: Culicidae) in Panama.

Authors:  J R Loaiza; E Bermingham; M E Scott; J R Rovira; J E Conn
Journal:  J Med Entomol       Date:  2008-09       Impact factor: 2.278

7.  Molecular Epidemiology of Plasmodium falciparum Malaria Outbreak, Tumbes, Peru, 2010-2012.

Authors:  G Christian Baldeviano; Sheila Akinyi Okoth; Nancy Arrospide; Rommell V Gonzalez; Juan F Sánchez; Silvia Macedo; Silvia Conde; L Lorena Tapia; Carola Salas; Dionicia Gamboa; Yeni Herrera; Kimberly A Edgel; Venkatachalam Udhayakumar; Andrés G Lescano
Journal:  Emerg Infect Dis       Date:  2015-05       Impact factor: 6.883

8.  Evaluation of dihydrofolate reductase and dihydropteroate synthetase genotypes that confer resistance to sulphadoxine-pyrimethamine in Plasmodium falciparum in Haiti.

Authors:  Tamar E Carter; Megan Warner; Connie J Mulligan; Alexander Existe; Yves S Victor; Gladys Memnon; Jacques Boncy; Roland Oscar; Mark M Fukuda; Bernard A Okech
Journal:  Malar J       Date:  2012-08-13       Impact factor: 2.979

9.  Importation of chloroquine-resistant Plasmodium falciparum by Guatemalan peacekeepers returning from the Democratic Republic of the Congo.

Authors:  Patricia C Juliao; Silvia Sosa; Luis D Gonzalez; Norma Padilla; Lucia Ortiz; Ira Goldman; Venkatachalam Udhayakumar; Kim A Lindblade
Journal:  Malar J       Date:  2013-09-23       Impact factor: 2.979

10.  Genetic structure of Plasmodium falciparum populations across the Honduras-Nicaragua border.

Authors:  Nerea Larrañaga; Rosa E Mejía; José I Hormaza; Alberto Montoya; Aida Soto; Gustavo A Fontecha
Journal:  Malar J       Date:  2013-10-04       Impact factor: 2.979
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