Literature DB >> 16280142

Steroidal saponins from roots of Asparagus officinalis.

Xuefeng Huang1, Lingyi Kong.   

Abstract

Sarsasapogenin M (1) and sarsasapogenin N (2), two new oligospirostanosides with a unique aglycone moiety, (25S)-5beta-spirostan-3beta, 17alpha-diol, along with seven known compounds (25S)-5beta-spirostan-3beta-ol-3-O-beta-d-glucopyranosyl-(1,2)-[beta-d-xylopyranosyl-(1,4)]-beta-d-glucopyranoside (3), (25S)-5beta-spirostan-3beta-ol-3-O-beta-d-glucopyranosyl-(1,2)-beta-d-glucopyranoside (4), (25S)-5beta-spirostan-3beta-ol-3-O-alpha-l-rhamnopyranosyl-(1,2)-[alpha-l-rhamnopyranosyl-(1,4)]-beta-d-glucopyranoside (5), (25S)26-O-beta-d-glucopyranosyl-5beta-furost-20 (22)-ene-3beta,26-diol-3-O-beta-d-glucopyranosyl-(1,2)-beta-d-glucopyranoside (6), yamogenin (7), beta-sitosterol (8), and sitosterol-beta-d-glucoside (9) were isolated from the roots of Asparagus officinalis L. Their structures were determined by spectral analysis, including extensive 1D and 2D NMR experiments.

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Year:  2005        PMID： 16280142     DOI： 10.1016/j.steroids.2005.09.005

Source DB:  PubMed          Journal:  Steroids        ISSN： 0039-128X            Impact factor:   2.668


  7 in total

1.  In vitro cytotoxic screening of selected Saudi medicinal plants.

Authors:  Hussein Almehdar; Hossam M Abdallah; Abdel-Moneim M Osman; Essam A Abdel-Sattar
Journal:  J Nat Med       Date:  2011-09-28       Impact factor: 2.343

2.  Anticancer effects of deproteinized asparagus polysaccharide on hepatocellular carcinoma in vitro and in vivo.

Authors:  Jianfeng Xiang; Yanjie Xiang; Shengming Lin; Dongwei Xin; Xiaoyu Liu; Lingling Weng; Tao Chen; Minguang Zhang
Journal:  Tumour Biol       Date:  2013-12-06

3.  Chemical analysis reveals the botanical origin of shatavari products and confirms the absence of alkaloid asparagamine A in Asparagus racemosus.

Authors:  Yukie Kumeta; Takuro Maruyama; Daigo Wakana; Hiroyuki Kamakura; Yukihiro Goda
Journal:  J Nat Med       Date:  2012-04-20       Impact factor: 2.343

Review 4.  Recent advances in steroidal saponins biosynthesis and in vitro production.

Authors:  Swati Upadhyay; Gajendra Singh Jeena; Rakesh Kumar Shukla
Journal:  Planta       Date:  2018-05-10       Impact factor: 4.116

5.  Methanolic extract of white asparagus shoots activates TRAIL apoptotic death pathway in human cancer cells and inhibits colon carcinogenesis in a preclinical model.

Authors:  Souad Bousserouel; Julie Le Grandois; Francine Gossé; Dalal Werner; Stephan W Barth; Eric Marchioni; Jacques Marescaux; Francis Raul
Journal:  Int J Oncol       Date:  2013-06-07       Impact factor: 5.650

Review 6.  Green and White Asparagus (Asparagus officinalis): A Source of Developmental, Chemical and Urinary Intrigue.

Authors:  Eirini Pegiou; Roland Mumm; Parag Acharya; Ric C H de Vos; Robert D Hall
Journal:  Metabolites       Date:  2019-12-25

7.  Asparagus cochinchinensis extract ameliorates menopausal depression in ovariectomized rats under chronic unpredictable mild stress.

Authors:  Hye Ryeong Kim; Young-Ju Lee; Tae-Wan Kim; Ri-Na Lim; Dae Youn Hwang; Jeffrey J Moffat; Soonil Kim; Joung-Wook Seo; Minhan Ka
Journal:  BMC Complement Med Ther       Date:  2020-10-27
  7 in total

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