| Literature DB >> 16278652 |
Hidetoshi Tahara1, Mayuko Kusunoki, Yusuke Yamanaka, Shusaku Matsumura, Toshinori Ide.
Abstract
Accurate measurement of telomeric 3'-overhang (G-tail) lengths is essential for investigation of the biological effects of telomere dysfunction. G-tail telomere hybridization protection assay (Gt-telomere HPA) has the advantages of being simple to perform, accurate and highly sensitive for G tails as short as 20 nucleotides. Furthermore, Gt-telomere HPA is specific and quantitative for human G tails, and can be used to assay cell lysates as well as genomic DNA.Entities:
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Year: 2005 PMID: 16278652 DOI: 10.1038/nmeth797
Source DB: PubMed Journal: Nat Methods ISSN: 1548-7091 Impact factor: 28.547