Literature DB >> 16277100

Prostate brachytherapy with iodine-125 seeds: radiation protection issues.

Silvia Anglesio1, Elisa Calamia, Christian Fiandra, Francesca Romana Giglioli, Riccardo Ragona, Umberto Ricardi, Roberto Ropolo.   

Abstract

AIMS AND
BACKGROUND: Brachytherapy for prostate cancer by means of permanently implanted 125I sources is a well established procedure. An increasing number of patients all over the world are treated with this modality. When the technique was introduced at our institution, radiation protection issues relative to this technique were investigated in order to comply with international recommendations and national regulations. Particular attention was paid to the need for patient shielding after discharge from hospital.
METHODS: The effective and equivalent doses to personnel related to implantation, the effective dose to patient relatives as computed by a developed algorithm, the air kerma strength values for the radioactive sources certified by the manufacturer compared with those measured by a well chamber, and the effectiveness of lead gloves in shielding the hands were evaluated.
RESULTS: The effective dose to the bodies of personnel protected by a lead apron proved to be negligible. The mean equivalent doses to the physician's hands was 420 microSv for one implant; the technician's hands received 65 microSv. The mean air kerma rate measured at the anterior skin surface of the patient who had received an implant was 55 microGy/h (range, 10-115) and was negligible with lead protection. The measured and certified air kerma strength for125I seeds in RAPID Strand corresponded within a margin of +/- 5%. The measured attenuation by lead gloves in operative conditions was about 80%. We also defined the recommendations to be given to the patient at discharge.
CONCLUSIONS: The exposure risks related to brachytherapy with 125I to operators and public are limited. However, alternation of operators should be considered to minimize exposure. Patient-related measurements should verify the dose rate around the patient to evaluate the need for shielding and to define appropriate radiation protection recommendations.

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Year:  2005        PMID: 16277100     DOI: 10.1177/030089160509100410

Source DB:  PubMed          Journal:  Tumori        ISSN: 0300-8916


  10 in total

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2.  Randomized comparison of long and short vascular sheaths in reduction of the operator radiation exposure during uterine artery embolization.

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3.  Clinical research on the treatment effects of radioactive (125)I seeds interstitial brachytherapy on children with primary orbital rhabdomyosarcoma.

Authors:  Xin Ge; Jianmin Ma; Haojie Dai; Ling Ren; Quan Li; Jitong Shi
Journal:  Med Oncol       Date:  2014-08-05       Impact factor: 3.064

4.  Clinical investigations on the spinal osteoblastic metastasis treated by combination of percutaneous vertebroplasty and (125)I seeds implantation versus radiotherapy.

Authors:  Zuozhang Yang; Jing Tan; Ruilian Zhao; Jiaping Wang; Hongpu Sun; Xiaoxue Wang; Lei Xu; Hua Jiang; Jinlei Zhang
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5.  Less-restrictive, patient-specific radiation safety precautions can be safely prescribed after permanent seed implantation.

Authors:  Lawrence T Dauer; Marisa A Kollmeier; Matthew J Williamson; Jean St Germain; Joaquin Altamirano; Yoshiya Yamada; Michael J Zelefsky
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Review 6.  Status and prospects of percutaneous vertebroplasty combined with ¹²⁵I seed implantation for the treatment of spinal metastases.

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7.  A novel perineal shield for low-dose-rate prostate brachytherapy.

Authors:  Joseph P Weiner; David Schwartz; Joseph Safdieh; Alex Polubarov; Tejas Telivala; Matthew Worth; David Schreiber
Journal:  J Contemp Brachytherapy       Date:  2015-06-08

8.  Clinical efficacy of computed tomography-guided iodine-125 seed implantation therapy in patients with advanced spinal metastatic tumors.

Authors:  Liyun Zhang; Jian Lu; Zhongmin Wang; Yingsheng Cheng; Gaojun Teng; Kemin Chen
Journal:  Onco Targets Ther       Date:  2015-12-18       Impact factor: 4.147

9.  Permanent Iodine-125 Seed Implantation for the Treatment of Nonresectable Retroperitoneal Malignant Tumors.

Authors:  Qingchun Li; Yuan Tian; Dongyan Yang; Yun Liang; Xianbin Cheng; Baodong Gai
Journal:  Technol Cancer Res Treat       Date:  2019-01-01

10.  Effectiveness of 125I seed implantation in the treatment of non-small cell lung cancer during R2 resection.

Authors:  Wei Li; Yifeng Zheng; Yunming Li; Jing Guan; Jianqing Jiang; Yongkang Yu; Xiushan Zheng; Lie Yang
Journal:  Oncol Lett       Date:  2017-09-21       Impact factor: 2.967

  10 in total

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