Literature DB >> 16275323

Expression and evaluation of RING finger proteins.

Yili Yang1, Kevin L Lorick, Jane P Jensen, Allan M Weissman.   

Abstract

RING finger proteins represent the largest class of potential ubiquitin ligases. This chapter describes methods used to express and assess the activity of proteins containing RING fingers based on our experience with a number of different family members. In addition to general protocols for assessing activity, specific protocols are provided for evaluating the ubiquitylation of p53 by the RING finger E3 Hdm2/Mdm2. Use of these methods may help identify new E3s, dissect factors involved in ubiquitylation of substrates, and screen for molecules that affect ubiquitylation.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 16275323     DOI： 10.1016/S0076-6879(05)98010-5

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


  8 in total

1.  Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha.

Authors:  Maritza Lienlaf; Fumiaki Hayashi; Francesca Di Nunzio; Naoya Tochio; Takanori Kigawa; Shigeyuki Yokoyama; Felipe Diaz-Griffero
Journal:  J Virol       Date:  2011-07-06       Impact factor: 5.103

Review 2.  The COP9 signalosome and cullin-RING ligases in the heart.

Authors:  Xuejun Wang; Douglas S Martin
Journal:  Am J Cardiovasc Dis       Date:  2015-03-20

Review 3.  The COP9 signalosome and vascular function: intriguing possibilities?

Authors:  Douglas S Martin; Xuejun Wang
Journal:  Am J Cardiovasc Dis       Date:  2015-03-20

4.  Trp53 regulates Notch 4 signaling through Mdm2.

Authors:  Youping Sun; Malgorzata Klauzinska; Robert J Lake; Joseph M Lee; Stefania Santopietro; Ahmed Raafat; David Salomon; Robert Callahan; Spyros Artavanis-Tsakonas
Journal:  J Cell Sci       Date:  2011-04-01       Impact factor: 5.285

5.  RNF-121 is an endoplasmic reticulum-membrane E3 ubiquitin ligase involved in the regulation of beta-integrin.

Authors:  Amir Darom; Ulrike Bening-Abu-Shach; Limor Broday
Journal:  Mol Biol Cell       Date:  2010-03-31       Impact factor: 4.138

6.  Virus-specific effects of TRIM5α(rh) RING domain functions on restriction of retroviruses.

Authors:  Xing Li; Jonghwa Kim; Byeongwoon Song; Andrés Finzi; Beatriz Pacheco; Joseph Sodroski
Journal:  J Virol       Date:  2013-05-01       Impact factor: 5.103

7.  Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis.

Authors:  Tobias Wauer; Kirby N Swatek; Jane L Wagstaff; Christina Gladkova; Jonathan N Pruneda; Martin A Michel; Malte Gersch; Christopher M Johnson; Stefan M V Freund; David Komander
Journal:  EMBO J       Date:  2014-12-19       Impact factor: 11.598

8.  Structure of the human Parkin ligase domain in an autoinhibited state.

Authors:  Tobias Wauer; David Komander
Journal:  EMBO J       Date:  2013-05-31       Impact factor: 11.598
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.