Literature DB >> 16268780

An analysis on gene architecture in human and mouse genomes.

Meena Kishore Sakharkar1, Bagavathi S Perumal, Kishore R Sakharkar, Pandjassarame Kangueane.   

Abstract

A comparative genome analysis on exon-intron distribution profiles is performed for human and mouse genomes to deduce similarities and differences between them. Interestingly, both in human and mouse genomes, the total length in introns and intergenic DNA on each chromosome is significantly correlated to the chromosome size. The results presented provide a framework for understanding the nature and patterns of exon-intron length distributions, the constraints on them and their role in genome design and evolution.

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Year:  2005        PMID: 16268780

Source DB:  PubMed          Journal:  In Silico Biol        ISSN: 1386-6338


  22 in total

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Journal:  Proc Natl Acad Sci U S A       Date:  2013-08-05       Impact factor: 11.205

2.  In silico analysis of the sequence features responsible for alternatively spliced introns in the model green alga Chlamydomonas reinhardtii.

Authors:  Praveen-Kumar Raj-Kumar; Olivier Vallon; Chun Liang
Journal:  Plant Mol Biol       Date:  2017-03-31       Impact factor: 4.076

Review 3.  Splicing and transcription touch base: co-transcriptional spliceosome assembly and function.

Authors:  Lydia Herzel; Diana S M Ottoz; Tara Alpert; Karla M Neugebauer
Journal:  Nat Rev Mol Cell Biol       Date:  2017-08-09       Impact factor: 94.444

4.  Dosage sensitivity and exon shuffling shape the landscape of polymorphic duplicates in Drosophila and humans.

Authors:  Dan Zhang; Liang Leng; Chunyan Chen; Jiawei Huang; Yaqiong Zhang; Hao Yuan; Chenyu Ma; Hua Chen; Yong E Zhang
Journal:  Nat Ecol Evol       Date:  2021-12-30       Impact factor: 15.460

5.  Intrasplicing coordinates alternative first exons with alternative splicing in the protein 4.1R gene.

Authors:  Marilyn K Parra; Jeff S Tan; Narla Mohandas; John G Conboy
Journal:  EMBO J       Date:  2007-12-13       Impact factor: 11.598

6.  Missense Mutations in NKAP Cause a Disorder of Transcriptional Regulation Characterized by Marfanoid Habitus and Cognitive Impairment.

Authors:  Sarah K Fiordaliso; Aiko Iwata-Otsubo; Alyssa L Ritter; Mathieu Quesnel-Vallières; Katsunori Fujiki; Eriko Nishi; Miroslava Hancarova; Noriko Miyake; Jenny E V Morton; Sangmoon Lee; Karl Hackmann; Masashige Bando; Koji Masuda; Ryuichiro Nakato; Michiko Arakawa; Elizabeth Bhoj; Dong Li; Hakon Hakonarson; Ryojun Takeda; Margaret Harr; Beth Keena; Elaine H Zackai; Nobuhiko Okamoto; Seiji Mizuno; Jung Min Ko; Alica Valachova; Darina Prchalova; Marketa Vlckova; Tommaso Pippucci; Christoph Seiler; Murim Choi; Naomichi Matsumoto; Nataliya Di Donato; Yoseph Barash; Zdenek Sedlacek; Katsuhiko Shirahige; Kosuke Izumi
Journal:  Am J Hum Genet       Date:  2019-10-03       Impact factor: 11.025

7.  Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5' splice site.

Authors:  Carsten Boesler; Norbert Rigo; Dmitry E Agafonov; Berthold Kastner; Henning Urlaub; Cindy L Will; Reinhard Lührmann
Journal:  RNA       Date:  2015-09-18       Impact factor: 4.942

8.  A comparison across non-model animals suggests an optimal sequencing depth for de novo transcriptome assembly.

Authors:  Warren R Francis; Lynne M Christianson; Rainer Kiko; Meghan L Powers; Nathan C Shaner; Steven H D Haddock
Journal:  BMC Genomics       Date:  2013-03-12       Impact factor: 3.969

9.  RNA structure is a key regulatory element in pathological ATM and CFTR pseudoexon inclusion events.

Authors:  Emanuele Buratti; Ashish Dhir; Marzena A Lewandowska; Francisco E Baralle
Journal:  Nucleic Acids Res       Date:  2007-06-18       Impact factor: 16.971

10.  Genome-wide target analysis of NEUROD2 provides new insights into regulation of cortical projection neuron migration and differentiation.

Authors:  Efil Bayam; Gulcan Semra Sahin; Gizem Guzelsoy; Gokhan Guner; Alkan Kabakcioglu; Gulayse Ince-Dunn
Journal:  BMC Genomics       Date:  2015-09-05       Impact factor: 3.969

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