Literature DB >> 16268544

A six-step asymmetric synthesis of (+)-hyperaspine.

Daniel L Comins1, James J Sahn.   

Abstract

[reaction: see text] The ladybird alkaloid, (+)-hyperaspine, has been synthesized in a concise and highly stereoselective manner. The total synthesis was accomplished in six steps and 21% overall yield.

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Year:  2005        PMID： 16268544     DOI： 10.1021/ol052068v

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  10 in total

1.  Synthesis of 6- and 7-membered cyclic enaminones: scope and mechanism.

Authors:  Micah J Niphakis; Brandon J Turunen; Gunda I Georg
Journal:  J Org Chem       Date:  2010-10-15       Impact factor: 4.354

2.  Natural Products and Their Mimics as Targets of Opportunity for Discovery.

Authors:  Stephen F Martin
Journal:  J Org Chem       Date:  2017-09-15       Impact factor: 4.354

3.  Enantioselective total synthesis of (-)-citrinadin A and revision of its stereochemical structure.

Authors:  Zhiguo Bian; Christopher C Marvin; Stephen F Martin
Journal:  J Am Chem Soc       Date:  2013-07-18       Impact factor: 15.419

Review 4.  Dearomatization strategies in the synthesis of complex natural products.

Authors:  Stéphane P Roche; John A Porco
Journal:  Angew Chem Int Ed Engl       Date:  2011-04-19       Impact factor: 15.336

5.  Palladium-catalyzed direct C-H arylation of cyclic enaminones with aryl iodides.

Authors:  Yi-Yun Yu; Lei Bi; Gunda I Georg
Journal:  J Org Chem       Date:  2013-06-10       Impact factor: 4.354

6.  Biomimetic Aerobic C-H Olefination of Cyclic Enaminones at Room Temperature: Development toward the Synthesis of 1,3,5-Trisubstituted Benzenes.

Authors:  Yi-Yun Yu; Gunda I Georg
Journal:  Adv Synth Catal       Date:  2014-04-14       Impact factor: 5.837

7.  N-acyldihydropyridones as synthetic intermediates. A stereoselective synthesis of acyclic amino alcohols containing multiple chiral centers.

Authors:  W Stephen McCall; Teresa Abad Grillo; Daniel L Comins
Journal:  J Org Chem       Date:  2008-12-19       Impact factor: 4.354

8.  Total synthesis of alkaloid 205B.

Authors:  Sergey V Tsukanov; Daniel L Comins
Journal:  J Org Chem       Date:  2014-09-17       Impact factor: 4.354

9.  Microwave-assisted synthesis of novel 2,3-dihydro-4-pyridinones.

Authors:  Bahjat A Saeed; Rita S Elias; Wisam A Radhi
Journal:  Molecules       Date:  2010-11-17       Impact factor: 4.411

10.  Enantioselective total syntheses of citrinadins A and B. Stereochemical revision of their assigned structures.

Authors:  Zhiguo Bian; Christopher C Marvin; Martin Pettersson; Stephen F Martin
Journal:  J Am Chem Soc       Date:  2014-09-29       Impact factor: 15.419
  10 in total

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