| Literature DB >> 16267312 |
Keri L Colabroy1, Tadhg P Begley.
Abstract
A new tryptophan catabolic pathway is characterized from Burkholderia cepacia J2315. In this pathway, tryptophan is converted to 2-amino-3-carboxymuconate semialdehyde, which is enzymatically degraded to pyruvate and acetate via the intermediates 2-aminomuconate and 4-oxalocrotonate. This pathway differs from the proposed mammalian pathway which converts 2-aminomuconate to 2-ketoadipate and, ultimately, glutaryl-coenzyme A.Entities:
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Year: 2005 PMID: 16267312 PMCID: PMC1280306 DOI: 10.1128/JB.187.22.7866-7869.2005
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490