Literature DB >> 1625818

Basic fibroblast growth factor (bFGF) acts centrally in the brain to inhibit gastric emptying in rats.

T Okumura1, A Uehara, S Kitamori, Y Watanabe, Y Taniguchi, K Tsuji, M Namiki.   

Abstract

In the present study, we evaluated the central nervous system action of basic fibroblast growth factor (bFGF) on gastric emptying of a liquid meal in conscious rats using a Phenol red method. Intracisternal injection of bFGF dose-dependently inhibited gastric emptying, while intraperitoneal injection of bFGF at the same doses failed to alter gastric emptying. These results suggest for the first time that bFGF acts in the central nervous system to delay gastric emptying.

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Year:  1992        PMID: 1625818     DOI: 10.1016/0304-3940(92)90296-j

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  1 in total

1.  Delayed gastric emptying by Helicobacter pylori lipopolysaccharide in conscious rats.

Authors:  T Okumura; E Shoji; N Takahashi; H Wakebe; K Imagawa; M Kikuchi; Y Kohgo
Journal:  Dig Dis Sci       Date:  1998-01       Impact factor: 3.199

  1 in total

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