Literature DB >> 16256141

Incidental findings in magnetic resonance imaging of the brains of healthy young men.

Frank Weber1, Heinz Knopf.   

Abstract

BACKGROUND AND
PURPOSE: To determine the frequency of serious intracranial abnormalities in a healthy young male population.
METHODS: Cranial MRI of 2,536 healthy young males, mean age 20.5 years, all applicants for military flying duties in the German Air Force.
RESULTS: The authors report a variety of morphological abnormalities in the brains of a large population of healthy young males, providing data on disease prevalence. Arachnoid cysts were found in 1.7% (95% CI 1.2 to 2.3%), vascular abnormalities in 0.51% (95% CI 0.29 to 0.9%), and intracranial tumors in 0.47% (95% CI 0.26 to 0.85%) of the applicants. No cerebral aneurysms were found.
CONCLUSION: The prevalence of primary brain tumors seems to be higher, whereas the prevalence of intracranial aneurysms is lower than expected. Only a small percentage of the detected abnormalities require urgent medical attention.

Entities:  

Mesh:

Year:  2005        PMID: 16256141     DOI: 10.1016/j.jns.2005.09.008

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN: 0022-510X            Impact factor:   3.181


  63 in total

1.  Incidental head and neck findings on MRI in young healthy volunteers: prevalence and clinical implications.

Authors:  L Reneman; M M L de Win; J Booij; W van den Brink; G J den Heeten; N Freling; C B L M Majoie
Journal:  AJNR Am J Neuroradiol       Date:  2012-06-21       Impact factor: 3.825

Review 2.  Incidental findings found in "healthy" volunteers during imaging performed for research: current legal and ethical implications.

Authors:  T C Booth; A Jackson; J M Wardlaw; S A Taylor; A D Waldman
Journal:  Br J Radiol       Date:  2010-03-24       Impact factor: 3.039

Review 3.  Incidental findings in imaging diagnostic tests: a systematic review.

Authors:  B Lumbreras; L Donat; I Hernández-Aguado
Journal:  Br J Radiol       Date:  2010-04       Impact factor: 3.039

4.  Ethics. Incidental findings in brain imaging research.

Authors:  Judy Illes; Matthew P Kirschen; Emmeline Edwards; L R Stanford; Peter Bandettini; Mildred K Cho; Paul J Ford; Gary H Glover; Jennifer Kulynych; Ruth Macklin; Daniel B Michael; Susan M Wolf
Journal:  Science       Date:  2006-02-10       Impact factor: 47.728

5.  An infected arachnoid cyst in an elderly patient.

Authors:  Vivek Sivaraman; Andrea Au-Yeung; Stefan Brew; Andrew W McEvoy; Richard Greenwood
Journal:  J Neurol       Date:  2008-02-21       Impact factor: 4.849

Review 6.  Practical approaches to incidental findings in brain imaging research.

Authors:  J Illes; M P Kirschen; E Edwards; P Bandettini; M K Cho; P J Ford; G H Glover; J Kulynych; R Macklin; D B Michael; S M Wolf; T Grabowski; B Seto
Journal:  Neurology       Date:  2008-01-29       Impact factor: 9.910

7.  The price of diagnosis.

Authors:  William Hamilton
Journal:  Br J Gen Pract       Date:  2008-12       Impact factor: 5.386

8.  Toward a uniform policy for handling incidental findings in neuroimaging research.

Authors:  D A Brown; A N Hasso
Journal:  AJNR Am J Neuroradiol       Date:  2008-08-07       Impact factor: 3.825

9.  The risks and benefits of searching for incidental findings in MRI research scans.

Authors:  Jason M Royal; Bradley S Peterson
Journal:  J Law Med Ethics       Date:  2008       Impact factor: 1.718

Review 10.  Bridging philosophical and practical implications of incidental findings in brain research.

Authors:  Judy Illes; Vivian Nora Chin
Journal:  J Law Med Ethics       Date:  2008       Impact factor: 1.718

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