Literature DB >> 16251330

Use of an efflux-deficient streptococcus pneumoniae strain panel to identify ABC-class multidrug transporters involved in intrinsic resistance to antimicrobial agents.

Gregory T Robertson1, Timothy B Doyle, A Simon Lynch.   

Abstract

Thirteen derivatives of the Streptococcus pneumoniae TIGR4 strain in which putative drug efflux pumps were genetically inactivated were constructed and characterized. The results indicate that two linked genes encoding the ABC-type transporters SP2073 and SP2075 function together to confer intrinsic resistance to a series of structurally unrelated compounds, including certain fluoroquinolones.

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Year:  2005        PMID： 16251330      PMCID： PMC1280156          DOI： 10.1128/AAC.49.11.4781-4783.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

1.  Non-PmrA-mediated multidrug resistance in Streptococcus pneumoniae.

Authors:  Ekaterina Pestova; John J Millichap; Farida Siddiqui; Gary A Noskin; Lance R Peterson
Journal:  J Antimicrob Chemother       Date:  2002-03       Impact factor: 5.790

2.  Identification of an efflux pump gene, pmrA, associated with fluoroquinolone resistance in Streptococcus pneumoniae.

Authors:  M J Gill; N P Brenwald; R Wise
Journal:  Antimicrob Agents Chemother       Date:  1999-01       Impact factor: 5.191

3.  Apparent involvement of a multidrug transporter in the fluoroquinolone resistance of Streptococcus pneumoniae.

Authors:  N N Baranova; A A Neyfakh
Journal:  Antimicrob Agents Chemother       Date:  1997-06       Impact factor: 5.191

4.  Isolation and characterization of three Streptococcus pneumoniae transformation-specific loci by use of a lacZ reporter insertion vector.

Authors:  E V Pestova; D A Morrison
Journal:  J Bacteriol       Date:  1998-05       Impact factor: 3.490

5.  Complete genome sequence of a virulent isolate of Streptococcus pneumoniae.

Authors:  H Tettelin; K E Nelson; I T Paulsen; J A Eisen; T D Read; S Peterson; J Heidelberg; R T DeBoy; D H Haft; R J Dodson; A S Durkin; M Gwinn; J F Kolonay; W C Nelson; J D Peterson; L A Umayam; O White; S L Salzberg; M R Lewis; D Radune; E Holtzapple; H Khouri; A M Wolf; T R Utterback; C L Hansen; L A McDonald; T V Feldblyum; S Angiuoli; T Dickinson; E K Hickey; I E Holt; B J Loftus; F Yang; H O Smith; J C Venter; B A Dougherty; D A Morrison; S K Hollingshead; C M Fraser
Journal:  Science       Date:  2001-07-20       Impact factor: 47.728

6.  Expression of efflux pump gene pmrA in fluoroquinolone-resistant and -susceptible clinical isolates of Streptococcus pneumoniae.

Authors:  Laura J V Piddock; Maggie M Johnson; S Simjee; L Pumbwe
Journal:  Antimicrob Agents Chemother       Date:  2002-03       Impact factor: 5.191

7.  Structure of the ABC transporter MsbA in complex with ADP.vanadate and lipopolysaccharide.

Authors:  Christopher L Reyes; Geoffrey Chang
Journal:  Science       Date:  2005-05-13       Impact factor: 47.728

8.  Prevalence of a putative efflux mechanism among fluoroquinolone-resistant clinical isolates of Streptococcus pneumoniae.

Authors:  N P Brenwald; M J Gill; R Wise
Journal:  Antimicrob Agents Chemother       Date:  1998-08       Impact factor: 5.191

9.  EfrAB, an ABC multidrug efflux pump in Enterococcus faecalis.

Authors:  Eun-Woo Lee; M Nazmul Huda; Teruo Kuroda; Tohru Mizushima; Tomofusa Tsuchiya
Journal:  Antimicrob Agents Chemother       Date:  2003-12       Impact factor: 5.191

10.  Update of practice guidelines for the management of community-acquired pneumonia in immunocompetent adults.

Authors:  Lionel A Mandell; John G Bartlett; Scott F Dowell; Thomas M File; Daniel M Musher; Cynthia Whitney
Journal:  Clin Infect Dis       Date:  2003-11-03       Impact factor: 9.079
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  29 in total

Review 1.  Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria.

Authors:  Laura J V Piddock
Journal:  Clin Microbiol Rev       Date:  2006-04       Impact factor: 26.132

2.  In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci.

Authors:  Seong Geun Hong; Ellen Smith Moland; Paul A Wickman; Jennifer A Black; Ashfaque Hossain; Nancy D Hanson; Kenneth S Thomson
Journal:  Antimicrob Agents Chemother       Date:  2007-01-12       Impact factor: 5.191

Review 3.  Efflux-mediated drug resistance in bacteria: an update.

Authors:  Xian-Zhi Li; Hiroshi Nikaido
Journal:  Drugs       Date:  2009-08-20       Impact factor: 9.546

Review 4.  Distribution and physiology of ABC-type transporters contributing to multidrug resistance in bacteria.

Authors:  Jacek Lubelski; Wil N Konings; Arnold J M Driessen
Journal:  Microbiol Mol Biol Rev       Date:  2007-09       Impact factor: 11.056

Review 5.  Xenobiotic efflux in bacteria and fungi: a genomics update.

Authors:  Ravi D Barabote; Jose Thekkiniath; Richard E Strauss; Govindsamy Vediyappan; Joe A Fralick; Michael J San Francisco
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  2011

Review 6.  Adaptive and mutational resistance: role of porins and efflux pumps in drug resistance.

Authors:  Lucía Fernández; Robert E W Hancock
Journal:  Clin Microbiol Rev       Date:  2012-10       Impact factor: 26.132

7.  Multiple mutations and increased RNA expression in tetracycline-resistant Streptococcus pneumoniae as determined by genome-wide DNA and mRNA sequencing.

Authors:  Andréanne Lupien; Hélène Gingras; Michel G Bergeron; Philippe Leprohon; Marc Ouellette
Journal:  J Antimicrob Chemother       Date:  2015-04-09       Impact factor: 5.790

8.  Genome sequencing of linezolid-resistant Streptococcus pneumoniae mutants reveals novel mechanisms of resistance.

Authors:  Jie Feng; Andréanne Lupien; Hélène Gingras; Jessica Wasserscheid; Ken Dewar; Danielle Légaré; Marc Ouellette
Journal:  Genome Res       Date:  2009-04-06       Impact factor: 9.043

9.  Genomic characterization of ciprofloxacin resistance in a laboratory-derived mutant and a clinical isolate of Streptococcus pneumoniae.

Authors:  Andréanne Lupien; Dewan S Billal; Fereshteh Fani; Hafid Soualhine; George G Zhanel; Philippe Leprohon; Marc Ouellette
Journal:  Antimicrob Agents Chemother       Date:  2013-07-22       Impact factor: 5.191

10.  The efflux pump inhibitor reserpine selects multidrug-resistant Streptococcus pneumoniae strains that overexpress the ABC transporters PatA and PatB.

Authors:  Mark I Garvey; Laura J V Piddock
Journal:  Antimicrob Agents Chemother       Date:  2008-03-24       Impact factor: 5.191
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