Literature DB >> 17220419

In vitro studies with DQ-113 and comparison fluoroquinolones to determine propensities to select resistance in gram-positive cocci.

Seong Geun Hong1, Ellen Smith Moland, Paul A Wickman, Jennifer A Black, Ashfaque Hossain, Nancy D Hanson, Kenneth S Thomson.   

Abstract

DQ-113 was compared in vitro to sitafloxacin, moxifloxacin, levofloxacin, and ciprofloxacin for potential to select mutational resistance in multiresistant staphylococci, pneumococci, and enterococci. Its ability to select less-susceptible mutants varied according to species, being lowest with staphylococci, intermediate with pneumococci, and greatest with enterococci.

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Year:  2007        PMID： 17220419      PMCID： PMC1855491          DOI： 10.1128/AAC.00959-06

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  9 in total

1.  Use of an efflux-deficient streptococcus pneumoniae strain panel to identify ABC-class multidrug transporters involved in intrinsic resistance to antimicrobial agents.

Authors:  Gregory T Robertson; Timothy B Doyle; A Simon Lynch
Journal:  Antimicrob Agents Chemother       Date:  2005-11       Impact factor: 5.191

2.  Involvement of the putative ATP-dependent efflux proteins PatA and PatB in fluoroquinolone resistance of a multidrug-resistant mutant of Streptococcus pneumoniae.

Authors:  Estelle Marrer; Karen Schad; Andreas T Satoh; Malcolm G P Page; Maggie M Johnson; Laura J V Piddock
Journal:  Antimicrob Agents Chemother       Date:  2006-02       Impact factor: 5.191

3.  Microbial Selection.

Authors:  V Bryson; W Szybalski
Journal:  Science       Date:  1952-07-18       Impact factor: 47.728

4.  Identification of an efflux pump gene, pmrA, associated with fluoroquinolone resistance in Streptococcus pneumoniae.

Authors:  M J Gill; N P Brenwald; R Wise
Journal:  Antimicrob Agents Chemother       Date:  1999-01       Impact factor: 5.191

5.  Genome of the bacterium Streptococcus pneumoniae strain R6.

Authors:  J Hoskins; W E Alborn; J Arnold; L C Blaszczak; S Burgett; B S DeHoff; S T Estrem; L Fritz; D J Fu; W Fuller; C Geringer; R Gilmour; J S Glass; H Khoja; A R Kraft; R E Lagace; D J LeBlanc; L N Lee; E J Lefkowitz; J Lu; P Matsushima; S M McAhren; M McHenney; K McLeaster; C W Mundy; T I Nicas; F H Norris; M O'Gara; R B Peery; G T Robertson; P Rockey; P M Sun; M E Winkler; Y Yang; M Young-Bellido; G Zhao; C A Zook; R H Baltz; S R Jaskunas; P R Rosteck; P L Skatrud; J I Glass
Journal:  J Bacteriol       Date:  2001-10       Impact factor: 3.490

6.  In vitro antibacterial activities of DQ-113, a potent quinolone, against clinical isolates.

Authors:  Mayumi Tanaka; Emi Yamazaki; Megumi Chiba; Kiyomi Yoshihara; Takaaki Akasaka; Makoto Takemura; Kenichi Sato
Journal:  Antimicrob Agents Chemother       Date:  2002-03       Impact factor: 5.191

7.  Prevalence of a putative efflux mechanism among fluoroquinolone-resistant clinical isolates of Streptococcus pneumoniae.

Authors:  N P Brenwald; M J Gill; R Wise
Journal:  Antimicrob Agents Chemother       Date:  1998-08       Impact factor: 5.191

8.  In vivo efficacy of a new quinolone, DQ-113, against Streptococcus pneumoniae in a mouse model.

Authors:  Yoshiko Otsu; Katsunori Yanagihara; Yuichi Fukuda; Yoshitsugu Miyazaki; Kazuhiro Tsukamoto; Yoichi Hirakata; Kazunori Tomono; Jun-ichi Kadota; Takayoshi Tashiro; Ikuo Murata; Shigeru Kohno
Journal:  Antimicrob Agents Chemother       Date:  2003-12       Impact factor: 5.191

9.  Effects of DQ-113, a new quinolone, against methicillin- and vancomycin-resistant Staphylococcus aureus-caused hematogenous pulmonary infections in mice.

Authors:  Yukihiro Kaneko; Katsunori Yanagihara; Yoshitsugu Miyazaki; Kazuhiro Tsukamoto; Yoichi Hirakata; Kazunori Tomono; Jun-ichi Kadota; Takayoshi Tashiro; Ikuo Murata; Shigeru Kohno
Journal:  Antimicrob Agents Chemother       Date:  2003-12       Impact factor: 5.191
  9 in total
  1 in total

Review 1.  Sitafloxacin: in bacterial infections.

Authors:  Gillian M Keating
Journal:  Drugs       Date:  2011-04-16       Impact factor: 9.546
  1 in total

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