Literature DB >> 1624939

Chemical investigation and anti-inflammatory activity of Vitex negundo seeds.

A S Chawla1, A K Sharma, S S Handa, K L Dhar.   

Abstract

The CHCl3 extract of the defatted seeds of Vitex negundo exhibited anti-inflammatory activity and yielded four triterpenoids: 3 beta-acetoxyolean-12-en-27-oic acid [1], 2 alpha, 3 alpha-dihydroxyoleana-5,12-dien-28-oic acid [2], 2 beta,3 alpha-diacetoxyoleana-5,12-dien-28-oic acid [3], and 2 alpha,3 beta-diacetoxy-18-hydroxyoleana-5,12-dien-28-oic acid [5]. This is the first report of the isolation of compounds 2, 3, and 5 from a natural source.

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Year:  1992        PMID： 1624939     DOI： 10.1021/np50080a002

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  6 in total

1.  Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases: "reverse pharmacology" and "bedside to bench" approach.

Authors:  Bharat B Aggarwal; Sahdeo Prasad; Simone Reuter; Ramaswamy Kannappan; Vivek R Yadev; Byoungduck Park; Ji Hye Kim; Subash C Gupta; Kanokkarn Phromnoi; Chitra Sundaram; Seema Prasad; Madan M Chaturvedi; Bokyung Sung
Journal:  Curr Drug Targets       Date:  2011-10       Impact factor: 3.465

2.  Constituents from Vitex negundo var. heterophylla and their inhibition of nitric oxide production.

Authors:  Chongyue Qiu; Liang Tong; Ting Yuan; Fei Wang; Feng Zhao; Lixia Chen
Journal:  J Nat Med       Date:  2016-08-17       Impact factor: 2.343

Review 3.  Vitex negundo and its medicinal value.

Authors:  Balraj Singh Gill; Richa Mehra; Sanjeev Kumar
Journal:  Mol Biol Rep       Date:  2018-10-11       Impact factor: 2.316

4.  Essential Oil Composition and Antibacterial Studies of Vitex negundo Linn. Extracts.

Authors:  S L Khokra; O Prakash; S Jain; K R Aneja; Yogita Dhingra
Journal:  Indian J Pharm Sci       Date:  2008 Jul-Aug       Impact factor: 0.975

5.  Bioactive chromone constituents from Vitex negundo alleviate pain and inflammation.

Authors:  Ajmal Khan; Sadia Naz; Umar Farooq; Muhammad Shahid; Irfan Ullah; Iftikhar Ali; Abdur Rauf; Yahia Nasser Mabkhot
Journal:  J Pain Res       Date:  2017-12-28       Impact factor: 3.133

6.  In silico to In vivo development of a polyherbal against Haemonchus contortus.

Authors:  Anu Rahal; D K Sharma; Ashok Kumar; Nitika Sharma; Deen Dayal
Journal:  Heliyon       Date:  2022-01-19
  6 in total

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