Literature DB >> 16248308

Flow in a mechanical bileaflet heart valve at laminar and near-peak systole flow rates: CFD simulations and experiments.

Liang Ge1, Hwa-Liang Leo, Fotis Sotiropoulos, Ajit P Yoganathan.   

Abstract

Time-accurate, fully 3D numerical simulations and particle image velocity laboratory experiments are carried out for flow through a fully open bileaflet mechanical heart valve under steady (nonpulsatile) inflow conditions. Flows at two different Reynolds numbers, one in the laminar regime and the other turbulent (near-peak systole flow rate), are investigated. A direct numerical simulation is carried out for the laminar flow case while the turbulent flow is investigated with two different unsteady statistical turbulence modeling approaches, unsteady Reynolds-averaged Navier-Stokes (URANS) and detached-eddy simulation (DES) approach. For both the laminar and turbulent cases the computed mean velocity profiles are in good overall agreement with the measurements. For the turbulent simulations, however, the comparisons with the measurements demonstrate clearly the superiority of the DES approach and underscore its potential as a powerful modeling tool of cardiovascular flows at physiological conditions. The study reveals numerous previously unknown features of the flow.

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Year:  2005        PMID: 16248308     DOI: 10.1115/1.1993665

Source DB:  PubMed          Journal:  J Biomech Eng        ISSN: 0148-0731            Impact factor:   2.097


  24 in total

1.  Measurements of steady flow through a bileaflet mechanical heart valve using stereoscopic PIV.

Authors:  Chris Hutchison; Pierre Sullivan; C Ross Ethier
Journal:  Med Biol Eng Comput       Date:  2010-11-16       Impact factor: 2.602

2.  Simulation of the fluid dynamics in artificial aortic roots: comparison of two different types of prostheses.

Authors:  Christoph L Bara; Janko F Verhey
Journal:  J Artif Organs       Date:  2008-10-05       Impact factor: 1.731

3.  Design of a pulsatile flow facility to evaluate thrombogenic potential of implantable cardiac devices.

Authors:  Sivakkumar Arjunon; Pablo Hidalgo Ardana; Neelakantan Saikrishnan; Shalv Madhani; Brent Foster; Ari Glezer; Ajit P Yoganathan
Journal:  J Biomech Eng       Date:  2015-02-11       Impact factor: 2.097

Review 4.  Review of numerical methods for simulation of mechanical heart valves and the potential for blood clotting.

Authors:  Mohamad Shukri Zakaria; Farzad Ismail; Masaaki Tamagawa; Ahmad Fazli Abdul Aziz; Surjatin Wiriadidjaja; Adi Azrif Basri; Kamarul Arifin Ahmad
Journal:  Med Biol Eng Comput       Date:  2017-07-26       Impact factor: 2.602

5.  The effect of inlet and outlet boundary conditions in image-based CFD modeling of aortic flow.

Authors:  Sudharsan Madhavan; Erica M Cherry Kemmerling
Journal:  Biomed Eng Online       Date:  2018-05-30       Impact factor: 2.819

6.  Modified control grid interpolation for the volumetric reconstruction of fluid flows.

Authors:  David H Frakes; Kerem Pekkan; Lakshmi P Dasi; Hiroumi D Kitajima; Diane de Zelicourt; Hwa Liang Leo; Josie Carberry; Kartik Sundareswaran; Helene Simon; Ajit P Yoganathan
Journal:  Exp Fluids       Date:  2008-12       Impact factor: 2.480

7.  Device Thrombogenicity Emulator (DTE)--design optimization methodology for cardiovascular devices: a study in two bileaflet MHV designs.

Authors:  Michalis Xenos; Gaurav Girdhar; Yared Alemu; Jolyon Jesty; Marvin Slepian; Shmuel Einav; Danny Bluestein
Journal:  J Biomech       Date:  2010-05-21       Impact factor: 2.712

8.  Original article submission: Platelet stress accumulation analysis to predict thrombogenicity of an artificial kidney.

Authors:  Amanda K W Buck; Steven G Goebel; Mark S Goodin; Nathan J Wright; Joseph J Groszek; Jarrett Moyer; Sukhveer Singh; Danny Bluestein; William H Fissell; Shuvo Roy
Journal:  J Biomech       Date:  2018-01-16       Impact factor: 2.712

9.  Combined In Silico and In Vitro Approach Predicts Low Wall Shear Stress Regions in a Hemofilter that Correlate with Thrombus Formation In Vivo.

Authors:  Amanda K W Buck; Joseph J Groszek; Daniel C Colvin; Sara B Keller; Clark Kensinger; Rachel Forbes; Seth Karp; Phillip Williams; Shuvo Roy; William H Fissell
Journal:  ASAIO J       Date:  2018 Mar/Apr       Impact factor: 2.872

10.  Impact of design parameters on bileaflet mechanical heart valve flow dynamics.

Authors:  Vijay Govindarajan; Holavanahalli S Udaykumar; Luke H Herbertson; Steven Deutsch; Keefe B Manning; Krishnan B Chandran
Journal:  J Heart Valve Dis       Date:  2009-09
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