Literature DB >> 1624372

A new anthelmintic cyclodepsipeptide, PF1022A.

T Sasaki1, M Takagi, T Yaguchi, S Miyadoh, T Okada, M Koyama.   

Abstract

The novel anthelmintic cyclodepsipeptide PF1022A was isolated from cultured mycelia of Mycelia Sterilia PF1022 (FERM BP-2671). It showed strong anthelmintic activities against Ascaridia galli in chickens. The structure of PF1022A was determined to be cyclo(D-lactyl-L-N-methylleucyl-D-3-phenyllactyl-L-N-meth ylleucyl-D-lactyl-L-N- methylleucyl-D-3-phenyllactyl-L-N-methylleucyl) by spectroscopic analyses and chemical studies.

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Year:  1992        PMID: 1624372     DOI: 10.7164/antibiotics.45.692

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  18 in total

1.  On the mode of action of emodepside: slow effects on membrane potential and voltage-activated currents in Ascaris suum.

Authors:  S K Buxton; C Neveu; C L Charvet; A P Robertson; R J Martin
Journal:  Br J Pharmacol       Date:  2011-09       Impact factor: 8.739

Review 2.  Emodepside and SL0-1 potassium channels: a review.

Authors:  R J Martin; S K Buxton; C Neveu; C L Charvet; A P Robertson
Journal:  Exp Parasitol       Date:  2011-09-03       Impact factor: 2.011

3.  Effects of PF1022A on adult Angiostrongylus cantonensis in the pulmonary arteries and larvae migrating into the central nervous system of rats.

Authors:  S Kachi; A Ishih; M Terada
Journal:  Parasitol Res       Date:  1995       Impact factor: 2.289

4.  A BRIEF REVIEW ON THE MODE OF ACTION OF ANTINEMATODAL DRUGS.

Authors:  Melanie Abongwa; Richard J Martin; Alan P Robertson
Journal:  Acta Vet (Beogr)       Date:  2017-06-26       Impact factor: 0.800

5.  SLO-1-channels of parasitic nematodes reconstitute locomotor behaviour and emodepside sensitivity in Caenorhabditis elegans slo-1 loss of function mutants.

Authors:  Claudia Welz; Nina Krüger; Monika Schniederjans; Sandra M Miltsch; Jürgen Krücken; Marcus Guest; Lindy Holden-Dye; Achim Harder; Georg von Samson-Himmelstjerna
Journal:  PLoS Pathog       Date:  2011-04-07       Impact factor: 6.823

6.  Potential drug development candidates for human soil-transmitted helminthiases.

Authors:  Piero Olliaro; Jürg Seiler; Annette Kuesel; John Horton; Jeffrey N Clark; Robert Don; Jennifer Keiser
Journal:  PLoS Negl Trop Dis       Date:  2011-06-07

7.  Aspersymmetide A, a New Centrosymmetric Cyclohexapeptide from the Marine-Derived Fungus Aspergillus versicolor.

Authors:  Xue-Mei Hou; Ya-Hui Zhang; Yang Hai; Ji-Yong Zheng; Yu-Cheng Gu; Chang-Yun Wang; Chang-Lun Shao
Journal:  Mar Drugs       Date:  2017-11-22       Impact factor: 5.118

8.  Efficacy evaluation of anthelmintic products against an infection with the canine hookworm (Ancylostoma caninum) isolate Worthy 4.1F3P in dogs.

Authors:  Pablo D Jimenez Castro; Abdelmoneim Mansour; Samuel Charles; Joe Hostetler; Terry Settje; Daniel Kulke; Ray M Kaplan
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2020-04-20       Impact factor: 4.077

9.  Cyclic Octamer Peptoids: Simplified Isosters of Bioactive Fungal Cyclodepsipeptides.

Authors:  Assunta D'Amato; Giorgio Della Sala; Irene Izzo; Chiara Costabile; Yuichi Masuda; Francesco De Riccardis
Journal:  Molecules       Date:  2018-07-19       Impact factor: 4.411

Review 10.  Development of emodepside as a possible adulticidal treatment for human onchocerciasis-The fruit of a successful industrial-academic collaboration.

Authors:  Jürgen Krücken; Lindy Holden-Dye; Jennifer Keiser; Roger K Prichard; Simon Townson; Benjamin L Makepeace; Marc P Hübner; Steffen R Hahnel; Ivan Scandale; Achim Harder; Daniel Kulke
Journal:  PLoS Pathog       Date:  2021-07-22       Impact factor: 6.823

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