Literature DB >> 1623966

The second human beta B2-crystallin gene is a pseudogene.

R H Brakenhoff1, H J Aarts, F Schuren, N H Lubsen, J G Schoenmakers.   

Abstract

Comparison of the partial sequences of the human beta B2-1- and beta B2-2-crystallin genes with orthologous rat or calf sequences shows that the fourth exon sequence of the human beta B2-2 gene contains a one triplet deletion and a mutated splice acceptor site. No transcripts from the beta B2-2-crystallin gene could be detected in the human lens. These data suggest that the human beta B2-2-crystallin gene is a pseudogene.

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Year:  1992        PMID： 1623966     DOI： 10.1016/0014-4835(92)90036-r

Source DB:  PubMed          Journal:  Exp Eye Res        ISSN： 0014-4835            Impact factor:   3.467


  3 in total

1.  Outcome Disparities in African American Compared with European American Women with ER+HER2- Tumors Treated within an Equal-Access Health Care System.

Authors:  Nicholas S Costantino; Benjamin Freeman; Craig D Shriver; Rachel E Ellsworth
Journal:  Ethn Dis       Date:  2016-07-21       Impact factor: 1.847

2.  Investigation of crystallin genes in familial cataract, and report of two disease associated mutations.

Authors:  K P Burdon; M G Wirth; D A Mackey; I M Russell-Eggitt; J E Craig; J E Elder; J L Dickinson; M M Sale
Journal:  Br J Ophthalmol       Date:  2004-01       Impact factor: 4.638

3.  Outcome disparities in African American women with triple negative breast cancer: a comparison of epidemiological and molecular factors between African American and Caucasian women with triple negative breast cancer.

Authors:  Lori A Sturtz; Jen Melley; Kim Mamula; Craig D Shriver; Rachel E Ellsworth
Journal:  BMC Cancer       Date:  2014-02-04       Impact factor: 4.430
  3 in total

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