Literature DB >> 16237818

Mechanic stimulation of the soles support zones as a countermeasure of the contractile properties decline under microgravity conditions.

D Khusnutdinova1, A Netreba, I Kozlovskaya.   

Abstract

Decrease in muscle contractility is an inevitable consequence of exposure in microgravity. A wealth of currently accumulated facts is indicative of profound modifications in structure and function of the skeletal muscles in the absence of gravity. Investigations with humans during space flights of varying duration (L.I. Kakurin et al., 1971; I.B. Kozlovskaya et al., 1984, 1987, 1991;.), ground-based simulation studies (A.M. Genin et al., 1969; L.S. Grigorieva et al., 1983), and numerous experiments with animals (E.I. IIyina-Kakueva et al., 1979; O.M. Edgerton et al 1991; B.S. Shenkman et al., 1994) made it evident that removal of gravitational loading is fraught with significant reductions in the contractile properties of muscular fibers, especially noticeable in muscles-extensors. Results of ground-based simulation studies led to the hypothesis that changes in muscle contractility developing already after few days in microgravity conditions are consequent to reduction in support afferentation that plays an important role in initiation and maintenance of the activity of tonic motor units (A.V. Kirenskaya et al., 1986). In view of the above, an idea has been proposed to prevent losses in tonic muscles contractility by application of artificial support. Testing of this hypothesis was the theme of the present investigation.

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Year:  2004        PMID: 16237818

Source DB:  PubMed          Journal:  J Gravit Physiol        ISSN: 1077-9248


  2 in total

Review 1.  Long-term dry immersion: review and prospects.

Authors:  Nastassia M Navasiolava; Marc-Antoine Custaud; Elena S Tomilovskaya; Irina M Larina; Tadaaki Mano; Guillemette Gauquelin-Koch; Claude Gharib; Inesa B Kozlovskaya
Journal:  Eur J Appl Physiol       Date:  2010-12-14       Impact factor: 3.078

2.  Plantar mechanical stimulation attenuates protein synthesis decline in disused skeletal muscle via modulation of nitric oxide level.

Authors:  Sergey A Tyganov; Ekaterina Mochalova; Svetlana Belova; Kristina Sharlo; Sergey Rozhkov; Vitaliy Kalashnikov; Olga Turtikova; Timur Mirzoev; Boris Shenkman
Journal:  Sci Rep       Date:  2021-05-07       Impact factor: 4.379

  2 in total

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