Literature DB >> 16235914

Stereoselective synthesis of pyrrolidines from N-allyl oxazolidines via hydrozirconation-cyclization.

Jean-Luc Vasse1, Antoine Joosten, Clément Denhez, Jan Szymoniak.   

Abstract

[reaction: see text] A new diastereoselective synthesis of pyrrolidines from readily available chiral N-allyl oxazolidines is presented. The construction of the pyrrolidine ring is achieved via a tandem hydrozirconation-stereoselective Lewis acid mediated cyclization sequence.

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Year:  2005        PMID： 16235914     DOI： 10.1021/ol0517776

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Enantioselective syntheses of both enantiomers of cis-pyrrolidine 225H.

Authors:  Hong Shu; April R Noble; Suhong Zhang; Lei Miao; Mark L Trudell
Journal:  Tetrahedron       Date:  2010-06       Impact factor: 2.457

2.  Asymmetric synthesis of polyfunctionalized pyrrolidines from sulfinimine-derived pyrrolidine 2-phosphonates. Synthesis of pyrrolidine 225C.

Authors:  Franklin A Davis; He Xu; Yongzhong Wu; Junyi Zhang
Journal:  Org Lett       Date:  2006-05-25       Impact factor: 6.005

3.  Diastereoselective C-H Bond Amination for Disubstituted Pyrrolidines.

Authors:  Diana A Iovan; Matthew J T Wilding; Yunjung Baek; Elisabeth T Hennessy; Theodore A Betley
Journal:  Angew Chem Int Ed Engl       Date:  2017-11-08       Impact factor: 15.336
  3 in total

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