| Literature DB >> 16233863 |
Shohei Nishimoto1, Mutsumi Takagi, Shigeyuki Wakitani, Takuya Nihira, Toshiomi Yoshida.
Abstract
The effect of glycosaminoglycan addition on a three-dimensional (3D) culture of porcine chondrocyte cells was investigated with a view to use in cartilage regenerative medicine. Chondroitin sulfate C increased the mRNA expression of type 2 collagen, while chondroitin sulfate A did not. Hyaluronic acid of high molecular weight markedly decreased the mRNA expression of both aggrecan and type 2 collagen, although hyaluronic acid of low molecular weight showed no apparent effect.Entities:
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Year: 2005 PMID: 16233863 DOI: 10.1263/jbb.100.123
Source DB: PubMed Journal: J Biosci Bioeng ISSN: 1347-4421 Impact factor: 2.894