Literature DB >> 1623061

Use of a synthetic protease inhibitor for the treatment of L-asparaginase-induced acute pancreatitis complicated by disseminated intravascular coagulation.

M Murakawa1, T Okamura, T Shibuya, M Harada, T Otsuka, Y Niho.   

Abstract

In two patients receiving L-asparaginase therapy, severe acute pancreatitis complicated by disseminated intravascular coagulation (DIC) developed. In both cases it was successfully treated with continuous infusion of a synthetic protease inhibitor, nafamostat mesilate. In this report, we briefly discuss the clinical efficacy of the synthetic protease inhibitor in treating such cases.

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Year:  1992        PMID： 1623061     DOI： 10.1007/bf01738305

Source DB:  PubMed          Journal:  Ann Hematol        ISSN： 0939-5555            Impact factor:   3.673


  26 in total

1.  Pharmacological studies of FUT-175, nafamostat mesilate. V. Effects on the pancreatic enzymes and experimental acute pancreatitis in rats.

Authors:  M Iwaki; Y Ino; A Motoyoshi; M Ozeki; T Sato; M Kurumi; T Aoyama
Journal:  Jpn J Pharmacol       Date:  1986-06

2.  Toxicity of E. coli L-asparaginase in man.

Authors:  H F Oettgen; P A Stephenson; M K Schwartz; R D Leeper; L Tallai; C C Tan; B D Clarkson; R B Golbey; I H Krakoff; D A Karnofsky; M L Murphy; J H Burchenal
Journal:  Cancer       Date:  1970-02       Impact factor: 6.860

3.  L-asparaginase: therapeutic and toxic effects in patients with neoplastic disease.

Authors:  C M Haskell; G P Canellos; B G Leventhal; P P Carbone; J B Block; A A Serpick; O S Selawry
Journal:  N Engl J Med       Date:  1969-11-06       Impact factor: 91.245

4.  Morbidity of acute pancreatitis: the effect of aprotinin and glucagon.

Authors: 
Journal:  Gut       Date:  1980-04       Impact factor: 23.059

5.  Management of asparaginase induced hemorrhagic pancreatitis complicated by pseudocyst.

Authors:  R Greenstein; C Nogeire; T Ohnuma; A Greenstein
Journal:  Cancer       Date:  1979-02       Impact factor: 6.860

6.  Toxic products in hemorrhagic ascitic fluid generated during experimental acute hemorrhagic pancreatitis in dogs and a treatment which reduces their effect.

Authors:  K Satake; I Koh; H Nishiwaki; K Umeyama
Journal:  Digestion       Date:  1985       Impact factor: 3.216

7.  Pancreatic pseudocyst complicating treatment of acute lymphoblastic leukemia.

Authors:  D A Caniano; A F Browne; E T Boles
Journal:  J Pediatr Surg       Date:  1985-08       Impact factor: 2.545

8.  Effects of FUT-175, a new synthetic protease inhibitor on endotoxin-induced disseminated intravascular coagulation in rats.

Authors:  T Yoshikawa; M Murakami; Y Furukawa; H Kato; S Takemura; M Kondo
Journal:  Haemostasis       Date:  1983

9.  New synthetic inhibitors of C1r, C1 esterase, thrombin, plasmin, kallikrein and trypsin.

Authors:  S Fujii; Y Hitomi
Journal:  Biochim Biophys Acta       Date:  1981-10-13

10.  Delayed pancreatic pseudocyst formations. Long-term complication of L-asparaginase treatment.

Authors:  S J Bertolone; M M Fuenfer; D B Groff; C C Patel
Journal:  Cancer       Date:  1982-12-15       Impact factor: 6.860
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2.  The specific inhibition of HepG2 cells proliferation by apoptosis induced by gabexate mesilate.

Authors:  Tsuneo Ozeki; Tsuneo Natori
Journal:  Int J Clin Exp Pathol       Date:  2010-08-15

3.  Complete gastric outlet obstruction following acid ingestion complicated by acute pancreatitis and disseminated intravascular coagulation.

Authors:  Z Ahmed; Z Mohyuddin
Journal:  Postgrad Med J       Date:  1997-07       Impact factor: 2.401

4.  Acute parotitis during induction therapy including L-asparaginase in acute lymphoblastic leukemia.

Authors:  S Sica; L Pagano; P Salutari; A Di Mario; S Rutella; G Leone
Journal:  Ann Hematol       Date:  1994-02       Impact factor: 3.673

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6.  Drug induced pancreatitis: A systematic review of case reports to determine potential drug associations.

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  7 in total

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